Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein [1-42]'
TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481160(US10906900, Reference 28)
Affinity DataKd:  1.20nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481159(US10906900, Reference 25c)
Affinity DataKd:  3.10nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481158(US10906900, Reference 25b)
Affinity DataKd:  4.27nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)
Affinity DataKd:  4.90nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)
Affinity DataKd:  16.8nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)
Affinity DataKd:  3.60nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKd:  1.68nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)
Affinity DataKd:  4.20nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)
Affinity DataKd:  11.8nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481150(US10906900, Reference 22b)
Affinity DataKd:  5.20nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481151(US10906900, Reference 22c)
Affinity DataKd:  2.90nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712709((R)-8-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 6.30nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50561738(CHEMBL4793969 | US12195470, Example 49)
Affinity DataIC50: 6.60nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50561734(CHEMBL4782495 | US12195470, Example 3)
Affinity DataIC50: 8.10nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50561739(CHEMBL4741478 | US12195470, Example 55)
Affinity DataIC50: 8.10nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50561736(CHEMBL4750933 | US12195470, Example 41)
Affinity DataIC50: 9.90nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50561737(CHEMBL4788632 | US12195470, Example 45)
Affinity DataIC50: 10.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712754((R)—N-((1R,5S,8s)-3-(6-methylpyrimidin-4-yl)-3-aza...)
Affinity DataIC50: 10.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712711((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 10.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712713((R)—N-((1R,5S,8s)-3-(6-methoxypyridazin-4-yl)-3-az...)
Affinity DataIC50: 11.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712750((R)-8-(3,4-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 11.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712708((R)—N-((1R,5S,8s)-3-(6-methoxypyridazin-4-yl)-3-az...)
Affinity DataIC50: 11.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712745((R)-7-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 11.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712722((R)-8-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataIC50: 11.9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712741((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 12.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712703((R)-7-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 12.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712758((R)—N-((1R,5S,8s)-3-(6-methylpyrimidin-4-yl)-3-aza...)
Affinity DataIC50: 13.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712760((R)-9-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 13.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712730((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 13.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712737((R)-7-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 15.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712724((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataIC50: 15.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712734((R)-7-(3,5-dichlorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 16nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712726((R)-7-(4-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 16.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712732((R)-8-(2,3-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 17.1nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712728((R)-7-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 17.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712749((R)—N-((1R,5S,8s)-3-(6-methylpyrimidin-4-yl)-3-aza...)
Affinity DataIC50: 17.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712715((R)-8-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 19.9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712748((R)-8-(3,5-dichlorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 20nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712736((R)-8-(2,4-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 21.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712735((R)-7-(3,5-dichlorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 22.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712740((R)-8-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 27.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712746((R)-7-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 27.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712744((R)-8-(4-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 28.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712753((R)-8-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 29.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712720((R)-8-(2,3-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 31.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712731((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 33.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712725((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataIC50: 33.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712742((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 34nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50561735(CHEMBL4793879 | US12195470, Example 8)
Affinity DataIC50: 34.1nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM712761((R)-9-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 34.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

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