Compile Data Set for Download or QSAR
Report error Found 120 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4/6'
TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515983(US11053238, Com. EX. 6)
Affinity DataIC50: 14nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515951(US11053238, Com. EX. 5)
Affinity DataIC50: 17nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 22nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 22nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM516039(US11053238, Compound 2a | US11053238, Compound 2b)
Affinity DataIC50: 22nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515904(4-(6-fluoro-1- methyl-1,2,3,4- tetrahydrobenzo[4,5...)
Affinity DataIC50: 23nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515904(4-(6-fluoro-1- methyl-1,2,3,4- tetrahydrobenzo[4,5...)
Affinity DataIC50: 23nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM516028(US11053238, Compound 1a | US11053238, Compound 1b)
Affinity DataIC50: 23nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM516275(US11053238, Compound 15b)
Affinity DataIC50: 23nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515905(N-(5-((4-ethylpiperazin- 1-yl)methyl) pyridin-2-yl...)
Affinity DataIC50: 31nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515923(US11053238, Compound 16b | US11053238, Example 16b)
Affinity DataIC50: 40nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515923(US11053238, Compound 16b | US11053238, Example 16b)
Affinity DataIC50: 45nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM516039(US11053238, Compound 2a | US11053238, Compound 2b)
Affinity DataIC50: 108nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM515986(US11053238, Com. EX. No. 7)
Affinity DataIC50: 110nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM516028(US11053238, Compound 1a | US11053238, Compound 1b)
Affinity DataIC50: 121nMAssay Description:To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648803(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(1- (...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648804(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648805(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(4-(4...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648806(3-cyclopropyl-1-(2-((1-(methylsulfonyl)piperidin- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648807(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-N-(5-(6...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648808(N-(1-(methylsulfonyl)piperidin-4-yl)-8-(8-oxa-2- a...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648811(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(5- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648813(US20240034731, Compound 102 | US20240034731, Compo...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648814(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-8-(8,8- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648815(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648817((3aR,8bR)-2-(2-((1-(methylsulfonyl)piperidin-4- yl...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648818(US20240034731, Compound 18 | 8-(1,1-difluoro-5-aza...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648821(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(1- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648822(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(5- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648823(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N-(2- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648824(N-(2-methylisoindolin-5-yl)-8-(7- (methylsulfonyl)...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648825(6-(2-((2-methylisoindolin-5-yl)amino)pyrido[3,4- d...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648826(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-6- methy...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648829(3-cyclopropyl-1-(6-methyl-2-((4-(6-methyl-2,6- dia...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648834(N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-6- methy...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648835(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-6- met...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648836(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-6- met...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648837(6-methyl-N-(4-(6-methyl-2,6- diazaspiro[3.3]heptan...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648842(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-N- ((1...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648843(8-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-6- met...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648852(1-(cyclopropanesulfonyl)-N-(8-{2,6- diazaspiro[3.4...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648853(N-(2-cyclopropylisoindolin-5-yl)-6-methyl-8-(2,6- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648856(N-(2-cyclopropylisoindolin-5-yl)-6- (difluoromethy...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648858(8-(1,1-difluoro-6-azaspiro[3.4]octan-6-yl)-6- meth...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648859(8-(2,2-difluoro-6-azaspiro[3.4]octan-6-yl)-6- meth...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648860(6-methyl-N-(1-(methylsulfonyl)piperidin-4-yl)-8- (...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648861(N-(1-((cyclobutylmethyl)sulfonyl)piperidin-4-yl)- ...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648862(3-cyclopropyl-1-(2-((1- (cyclopropylsulfonyl)piper...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 4/6(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM648863(8-(3-cyclopropoxyazetidin-1-yl)-N-(1- (cyclopropyl...)
Affinity DataIC50: 200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent

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