Compile Data Set for Download or QSAR
Report error Found 292 Enz. Inhib. hit(s) with Target = 'Dopamine beta-hydroxylase'
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014978(CHEMBL433493 | 1-(3,5-Difluoro-4-hydroxy-benzyl)-1...)
Affinity DataKi:  5.70nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014970(CHEMBL351873 | 4-(3,5-Difluoro-4-hydroxy-benzyl)-2...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50548688(CHEMBL4764135)
Affinity DataIC50: 39nMAssay Description:Inhibition of bovine adrenal medulla DBH incubated for 25 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataKi:  41nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataIC50: 50nMAssay Description:Inhibition of bovine adrenal medulla DBH incubated for 25 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014968(CHEMBL164747 | 4-(2-Mercapto-imidazol-1-ylmethyl)-...)
Affinity DataKi:  55nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014968(CHEMBL164747 | 4-(2-Mercapto-imidazol-1-ylmethyl)-...)
Affinity DataKi:  55nMpH: 4.5Assay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014978(CHEMBL433493 | 1-(3,5-Difluoro-4-hydroxy-benzyl)-1...)
Affinity DataIC50: 74nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50014978(CHEMBL433493 | 1-(3,5-Difluoro-4-hydroxy-benzyl)-1...)
Affinity DataIC50: 74nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014978(CHEMBL433493 | 1-(3,5-Difluoro-4-hydroxy-benzyl)-1...)
Affinity DataIC50: 74nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.060-0.0877).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014978(CHEMBL433493 | 1-(3,5-Difluoro-4-hydroxy-benzyl)-1...)
Affinity DataIC50: 74.1nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014978(CHEMBL433493 | 1-(3,5-Difluoro-4-hydroxy-benzyl)-1...)
Affinity DataIC50: 74.1nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50015622(CHEMBL275322 | 1-(2-Thiophen-2-yl-ethyl)-1,3-dihyd...)
Affinity DataIC50: 114nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50015620(CHEMBL54434 | 1-(2-Thiophen-3-yl-ethyl)-1,3-dihydr...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataKi:  149nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataKi:  149nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014968(CHEMBL164747 | 4-(2-Mercapto-imidazol-1-ylmethyl)-...)
Affinity DataKi:  344nMpH: 6.6Assay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 6.6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50015617(CHEMBL54906 | 1-[2-(5-Methyl-thiophen-2-yl)-ethyl]...)
Affinity DataIC50: 491nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014963(CHEMBL165242 | 1-(3,5-Difluoro-4-hydroxy-benzyl)-1...)
Affinity DataIC50: 660nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50025811(1-(3,5-Dichloro-4-hydroxy-benzyl)-1,3-dihydro-imid...)
Affinity DataIC50: 676nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025811(1-(3,5-Dichloro-4-hydroxy-benzyl)-1,3-dihydro-imid...)
Affinity DataIC50: 676nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025811(1-(3,5-Dichloro-4-hydroxy-benzyl)-1,3-dihydro-imid...)
Affinity DataIC50: 676nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50025811(1-(3,5-Dichloro-4-hydroxy-benzyl)-1,3-dihydro-imid...)
Affinity DataIC50: 680nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (25-81).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 0.4-1.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50015621(CHEMBL55949 | 1-(5-Chloro-thiophen-2-ylmethyl)-1,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014984(CHEMBL165150 | 4-(3,5-Difluoro-benzyl)-2,4-dihydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 1.1-1.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.0-1.9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014983(CHEMBL278068 | 1-(3,5-Difluoro-benzyl)-1,3-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014971(CHEMBL352449 | 1-(3,5-Difluoro-benzyl)-imidazolidi...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50025795(1-(3-Fluoro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.9-2.2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025795(1-(3-Fluoro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025795(1-(3-Fluoro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50025795(1-(3-Fluoro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014967(CHEMBL165032 | 1-(3,5-Difluoro-benzyl)-1H-tetrazol...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50015619(CHEMBL54500 | 1-(3-Thiophen-2-yl-propyl)-1,3-dihyd...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50014979(CHEMBL165206 | 4-(3-Fluoro-benzyl)-2,4-dihydro-[1,...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase (DBH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50025806(1-(3-Chloro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025806(1-(3-Chloro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025806(1-(3-Chloro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50236983(2-hydroxycyclohepta-2,4,6-trienone | tropolone | 2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dopamine beta-oxygenase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50025806(1-(3-Chloro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.7-2.4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50498342(CHEMBL3357560)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dopamine beta-oxygenase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50025798(1-[3-(3,5-Dichloro-phenyl)-propyl]-1,3-dihydro-imi...)
Affinity DataIC50: 2.10E+3nMAssay Description:Percent inhibition against bovine Dopamine beta hydroxylase at 10E-4 M concentration of the compound; Range is between (1.8-2.6).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  2.18E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetDopamine beta-hydroxylase(Human)
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50025803(1-(3,4-Dihydroxy-benzyl)-1,3-dihydro-imidazole-2-t...)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
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