Compile Data Set for Download or QSAR
Report error Found 115 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2 [23-127]'
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432016BDBM432016(US10576064, Example I-238 | US10576064, Example I-...)
Affinity DataIC50: 2nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432016BDBM432016(US10576064, Example I-238 | US10576064, Example I-...)
Affinity DataIC50: 2nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431985BDBM431985(US10576064, Example I-186 | US10576064, Example I-...)
Affinity DataIC50: 2nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432043BDBM432043(US10576064, Example I-284)
Affinity DataIC50: 3nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431985BDBM431985(US10576064, Example I-186 | US10576064, Example I-...)
Affinity DataIC50: 3nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431975BDBM431975(US10576064, Example I-171 | US10576064, Example I-...)
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432042BDBM432042(US10576064, Example I-283)
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432021BDBM432021(US10576064, Example I-244)
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432019BDBM432019(US10576064, Example I-240)
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432028BDBM432028(US10576064, Example I-258)
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432011BDBM432011(US10576064, Example I-230)
Affinity DataIC50: 5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432009BDBM432009(US10576064, Example I-229 | US10576064, Example I-...)
Affinity DataIC50: 5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432001BDBM432001(US10576064, Example I-217 | US10576064, Example I-...)
Affinity DataIC50: 5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432030BDBM432030(US10576064, Example I-261)
Affinity DataIC50: 5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432001BDBM432001(US10576064, Example I-217 | US10576064, Example I-...)
Affinity DataIC50: 6nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432040BDBM432040(US10576064, Example I-280)
Affinity DataIC50: 7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432005BDBM432005(US10576064, Example I-221)
Affinity DataIC50: 7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431955BDBM431955(US10576064, Example I-43)
Affinity DataIC50: 8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432044BDBM432044(US10576064, Example I-285)
Affinity DataIC50: 8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432047BDBM432047(US10576064, Example I-288)
Affinity DataIC50: 8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432046BDBM432046(US10576064, Example I-287)
Affinity DataIC50: 8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432025BDBM432025(US10576064, Example I-252)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432024BDBM432024(US10576064, Example I-250)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432026BDBM432026(US10576064, Example I-254)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432013BDBM432013(US10576064, Example I-233)
Affinity DataIC50: 9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431984BDBM431984(US10576064, Example I-183)
Affinity DataIC50: 10nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432045BDBM432045(US10576064, Example I-286)
Affinity DataIC50: 10nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432009BDBM432009(US10576064, Example I-229 | US10576064, Example I-...)
Affinity DataIC50: 11nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431975BDBM431975(US10576064, Example I-171 | US10576064, Example I-...)
Affinity DataIC50: 11nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432029BDBM432029(US10576064, Example I-259)
Affinity DataIC50: 11nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432008BDBM432008(US10576064, Example I-226)
Affinity DataIC50: 12nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432012BDBM432012(US10576064, Example I-231)
Affinity DataIC50: 12nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431995BDBM431995(US10576064, Example I-204)
Affinity DataIC50: 15nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431987BDBM431987(US10576064, Example I-188)
Affinity DataIC50: 16nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431981BDBM431981(US10576064, Example I-177)
Affinity DataIC50: 16nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431939BDBM431939(US10576064, Example I-5)
Affinity DataIC50: 17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431960BDBM431960(US10576064, Example I-72)
Affinity DataIC50: 17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432007BDBM432007(US10576064, Example I-224)
Affinity DataIC50: 17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432022BDBM432022(US10576064, Example I-246)
Affinity DataIC50: 17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432033BDBM432033(US10576064, Example I-266)
Affinity DataIC50: 19nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432037BDBM432037(US10576064, Example I-274)
Affinity DataIC50: 20nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431991BDBM431991(US10576064, Example I-196)
Affinity DataIC50: 20nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431999BDBM431999(US10576064, Example I-212)
Affinity DataIC50: 21nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432031BDBM432031(US10576064, Example I-262)
Affinity DataIC50: 21nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432036BDBM432036(US10576064, Example I-272)
Affinity DataIC50: 25nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432034BDBM432034(US10576064, Example I-268)
Affinity DataIC50: 26nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431992BDBM431992(US10576064, Example I-198)
Affinity DataIC50: 27nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432027BDBM432027(US10576064, Example I-256)
Affinity DataIC50: 27nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 432035BDBM432035(US10576064, Example I-270)
Affinity DataIC50: 27nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 431979BDBM431979(US10576064, Example I-173)
Affinity DataIC50: 29nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

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