Compile Data Set for Download or QSAR
Report error Found 234 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP [265-330]'
TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783241(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((1,2- p...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783298(N,N-(1,4- phenylenebis(methylene)) bis(2-(1-(((2R,...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783373((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783211(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)- terephth...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783242(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(([1,1'- ...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783207(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- (m...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783266(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((2,4- d...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783272(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((1,3- p...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783198(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-(2,2'- ((...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783209(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-([2,2'- b...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783296(N1,N4-bis(2-(1- (((2R,5R)-1-(2-(6-(4- fluorobenzyl...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783210(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)- (naphtha...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783267(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((4-fluo...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783215(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-([2,2'- b...)
Affinity DataIC50: 5.35nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783257(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((1,4- p...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783217(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2R,2'R)-decane-1,...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783315((2S,2'S)-N,N'- (piperazine-1,4- diylbis(propane-3,...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783256(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-((hexane-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783351((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783271(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((2-meth...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783294(2,2'-(1,4- phenylene)bis(N-((1- (((2R,5R)-1-(2-(6-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783259(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(([1,1'- ...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783282((2S,2'S)-N,N-(hexane- 1,6-diyl)bis(4- (((2R,5R)-1-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783350(6-(4-fluorobenzyl)-1- (2-((2R,5R)-2-(((R)-4- (2-(1...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783270(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(([1,1'- ...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783293(N1,N4-bis((1- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783316((2S,2'S)-N,N'-(hexane- 1,6-diyl)bis(4- (((2R,5R)-1...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783290(N-((1-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783313((2S,2'S)-N,N'- (((oxybis(ethane-2,1- diyl))bis(oxy...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783214(1,5-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783346(6-(4-fluorobenzyl)-1- (2-((2R,5R)-2-(((R)-4- (2-(1...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783289(N-((1-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783280(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((2-chlo...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783291(2,2'-(1,4- phenylene)bis(N-((1- (((2R,5R)-1-(2-(6-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783279(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(((2-brom...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783310(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-(piperazi...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783355((2S,2'S)-N,N'-(1,4- phenylenebis(methylen e))bis(4...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783287(N1,N3-bis((1- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783297(N,N-(1,4- phenylenebis(methylene)) bis(2-(1-(((2R,...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783299(1,1'-(2,2'- ((3R,3'R,6R,6'R)- ((((1,3- phenylenebi...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783311((2S,2'S)-N,N-(octane- 1,8-diyl)bis(4- (((2R,5R)-1-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783322((2S,2'S)-N,N-(propane- 1,3-diyl)bis(4- (((2R,5R)-1...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783356((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783288(N1,N4-bis((1- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783284((2S,2'S)-N,N-((1S,4S)- cyclohexane-1,4- diyl)bis(4...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783352((S)-4-(((2R,5R)-1-(2- (6-(4-fluorobenzyl)- 3,3-dim...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783295(N1,N4-bis(2-(1- (((2R,5R)-1-(2-(6-(4- fluorobenzyl...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783318((2S,2'S)-N,N-(butane- 1,4-diyl)bis(4- (((2R,5R)-1-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783260(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)- (((oxybi...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783283((2S,2'S)-N,N-(1,4- phenylenebis(methylene)) bis(4-...)
Affinity DataIC50: 15.8nMAssay Description:The BIR domain binding assays are FRET based competition assays that utilize His-tagged versions of each of the BIR2 and BIR3 domains from cIAP1, cIA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

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