Compile Data Set for Download or QSAR
Report error Found 749 Enz. Inhib. hit(s) with Target = 'Epoxide hydrolase'
TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409020(US10377744, Compound No. 40 | US11123311, Compound...)
Affinity DataKi: <0.0500nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409007(US10377744, Compound No. 28 | US11723929, Compound...)
Affinity DataKi:  0.0500nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409005(US10377744, Compound No. 26 | US11123311, Compound...)
Affinity DataKi: <0.0500nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409009(US10377744, Compound No. 30 | US11123311, Compound...)
Affinity DataKi: <0.0500nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409030(US10377744, Compound No. 51 | US11123311, Compound...)
Affinity DataKi:  0.0600nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409016(US10377744, Compound No. 36 | US11123311, Compound...)
Affinity DataKi:  0.0800nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409003(US10377744, Compound No. 24 | US11123311, Compound...)
Affinity DataKi:  0.150nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408992(US10377744, Compound No. 14 | US10377744, Compound...)
Affinity DataKi:  0.220nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408986(US10377744, Compound No. 7 | US11123311, Compound ...)
Affinity DataKi:  0.260nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408998(US10377744, Compound No. 19 | US11123311, Compound...)
Affinity DataKi:  0.310nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408982(US10377744, Compound No. 3 | US11123311, Compound ...)
Affinity DataKi:  0.330nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409014(US10377744, Syn34 | US10377744, Compound No. 34 | ...)
Affinity DataKi:  0.370nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409021(US10377744, Compound No. 41 | US11123311, Compound...)
Affinity DataKi:  0.380nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409012(US10377744, Compound No. 32 | US11123311, Compound...)
Affinity DataKi:  0.380nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591330(CHEMBL5197431 | US20240182406, Example C11)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50327850(US8501783, 1711 | CHEMBL1257759 | 1-(1-Tosylpiperi...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50581727(CHEMBL5084744 | US20240182406, Example 2)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591340(CHEMBL5203787 | US20240182406, Example 4)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591334(CHEMBL5191146 | US20240182406, Example 3)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591337(CHEMBL5192445 | US20240182406, Example 10)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM2197(US8501783, 1591)
Affinity DataIC50: 0.400nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM679460(1-(9-chloro-2,3-dimethoxy-5,6,8,9,10,11-hexahydro-...)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591336(CHEMBL5179027 | US20240182406, Example 8)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591341(CHEMBL5177372 | US20240182406, Example 7)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50327847(CHEMBL1257517 | US8501783, 1591 | 1-(1-(Trifluoroa...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591331(CHEMBL5197282 | US20240182406, Example C3)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM679468(4-(4-(3-(9-chloro-5,6,8,9,10,11-hexahydro-7H-5,9:7...)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM679469(4-(4-(3-(9-chloro-5,6,8,9,10,11-hexahydro-7H-5,9:7...)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408999(US10377744, Compound No. 20 | US11123311, Compound...)
Affinity DataKi:  0.490nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408995(US10377744, Compound No. 16 | US11123311, Compound...)
Affinity DataKi:  0.5nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50581728(CHEMBL5093683 | US20240182406, Example 1)
Affinity DataIC50: 0.5nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM679467(4-(4-(3-(9-fluoro-5,6,8,9,10,11-hexahydro-7H-5,9:7...)
Affinity DataIC50: 0.5nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408992(US10377744, Compound No. 14 | US10377744, Compound...)
Affinity DataKi:  0.510nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408985(US10377744, Compound No. 6 | US11123311, Compound ...)
Affinity DataKi:  0.550nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591338(CHEMBL5203245 | US20240182406, Example 9)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591333(CHEMBL5197313 | US20240182406, Example 12)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50591335(CHEMBL5179500 | US20240182406, Example 11)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM679459(1-(9-fluoro-2,3-dimethoxy-5,6,8,9,10,11-hexahydro-...)
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408981(US10377744, Compound No. 2 | US11123311, Compound ...)
Affinity DataKi:  0.640nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409023(US10377744, Compound No. 43 | US11123311, Compound...)
Affinity DataKi:  0.700nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409004(US10377744, Compound No. 25 | US11123311, Compound...)
Affinity DataKi:  0.700nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409008(US10377744, Compound No. 29 | US11123311, Compound...)
Affinity DataKi:  0.75nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM408984(US10377744, Compound No. 5 | US11123311, Compound ...)
Affinity DataKi:  0.770nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409006(US10377744, Compound No. 27 | US11123311, Compound...)
Affinity DataKi:  0.780nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50327856(CHEMBL1257880 | US8501783, 1710 | 1-(1-(5-(Dimethy...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM409002(US10377744, Compound No. 23 | US11123311, Compound...)
Affinity DataKi:  0.870nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM100436(US8501783, 1702)
Affinity DataIC50: 0.900nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM679478(1-(1-acetylpiperidin-4-yl)-3-(1-fluoro-9-methyl-5,...)
Affinity DataIC50: 0.900nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM679477(1-(1-acetylpiperidin-4-yl)-3-(2-fluoro-9-methyl-5,...)
Affinity DataIC50: 0.900nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50551715(CHEMBL4741234)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of tissue extract derived mEH (unknown origin) using [3H]trans-stilbene oxide as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
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