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Report error Found 420 Enz. Inhib. hit(s) with Target = 'Equilibrative nucleoside transporter 1'
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301066(N-(6-(2-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(4-nitr...)
Affinity DataKi:  0.0180nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in HL60 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301067(N-(6-(2-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(4-nitr...)
Affinity DataKi:  0.0640nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in HL60 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301068(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)
Affinity DataKd:  0.260nMAssay Description:Binding affinity to human ENT1 in HL60 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Rat)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301068(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)
Affinity DataKd:  0.320nMAssay Description:Binding affinity to human ENT1 in Capan1 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301068(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)
Affinity DataKd:  0.360nMAssay Description:Binding affinity to human ENT1 in BX-PC3 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301068(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to human ENT1 in SK-PC1 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.430nM ΔG°:  -52.9kJ/mole IC50: 7.60nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50376975(CHEMBL260570)
Affinity DataKi:  0.450nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from human ENT1 transporter in human K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370291(CHEMBL608208)
Affinity DataKi:  0.450nMAssay Description:Binding affinity of compound towards Nucleoside transporter es-type by facile competitive binding flow cytometric assay using the human K562 chronic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23631(2-{[4,8-bis(azocan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Affinity DataKi:  0.490nM ΔG°:  -52.6kJ/mole IC50: 8.67nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370560(CHEMBL610234)
Affinity DataKi:  0.640nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human ENT1 assessed as [3H]uridine uptake by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in K562 cells after 45 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of compound towards Nucleoside transporter es-type by facile competitive binding flow cytometric assay using the human K562 chronic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from human ENT1 transporter in human K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from K562 cell nucleoside transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.708nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23633(2-{[4,8-bis(azonan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Affinity DataKi:  0.770nM ΔG°:  -51.5kJ/mole IC50: 13.6nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23629(2-{[4,8-bis(azepan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Affinity DataKi:  0.860nM ΔG°:  -51.2kJ/mole IC50: 15.2nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301068(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)
Affinity DataKd:  0.910nMAssay Description:Binding affinity to human ENT1 in MIA-PaCa2 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370567(CHEMBL608795)
Affinity DataKi:  0.940nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ENT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50222744(2-amino-6-(4-nitrobenzylthio)-9-beta-D-ribofuranos...)
Affinity DataKi:  1.10nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in K562 cells after 45 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301066(N-(6-(2-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(4-nitr...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in HL60 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50413751(CHEMBL61773)
Affinity DataKi:  1.78nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50222749(2-fluoro-6-(4-nitrobenzylthio)-9-beta-D-ribofurano...)
Affinity DataKi:  2.10nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in K562 cells after 45 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370565(CHEMBL610047)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50412033(CHEMBL260688)
Affinity DataIC50: 2.75nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50036307(CHEMBL3353069)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370557(CHEMBL607955)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50036309(CHEMBL3353072)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370568(CHEMBL610236)
Affinity DataKi:  3.60nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370562(CHEMBL610235)
Affinity DataKi:  3.70nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301068(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to human ENT1 in panc1 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50366947(CHEMBL512162 | BDBM50413737 | CHEMBL610941)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50366947(CHEMBL512162 | BDBM50413737 | CHEMBL610941)
Affinity DataKi:  3.90nMAssay Description:Displacement of 5-(SAENTA)-X8-fluorescein from K562 cell nucleoside transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23697(2-({6-[(2-hydroxyethyl)[2-(propan-2-yloxy)ethyl]am...)
Affinity DataKi:  4.30nM IC50: 76nMAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50413747(CHEMBL61741)
Affinity DataKi:  4.37nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50413740(CHEMBL61915)
Affinity DataKi:  4.57nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50036311(CHEMBL3353074)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50412008(CHEMBL259866)
Affinity DataIC50: 4.79nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50301067(N-(6-(2-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(4-nitr...)
Affinity DataIC50: 5.10nMAssay Description:Displacement of SAENTA-fluorescein from human ENT1 in HL60 cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370563(CHEMBL609378)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50370566(CHEMBL608794)
Affinity DataKi:  5.40nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50376975(CHEMBL260570)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM50413744(CHEMBL432688)
Affinity DataKi:  7.08nMAssay Description:Inhibition of human ENT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataKi:  8.18nM ΔG°:  -45.7kJ/mole IC50: 145nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23692({2-[(6-{bis[2-(formyloxy)ethyl]amino}-4,8-bis(pipe...)
Affinity DataKi:  8.20nM IC50: 145nMAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Ulm University

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataIC50: 8.51nMAssay Description:Binding affinity to ENT1 transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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