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Report error Found 67 Enz. Inhib. hit(s) with Target = 'Folylpolyglutamate synthase, mitochondrial'
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116252(2-[(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 20nMAssay Description:Compound was evaluated for its ability to inhibit Folyl-poly-gamma-glutamyl synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116250(2-[(3-Carboxy-3-{4-[(2,4-diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 120nMAssay Description:Compound was evaluated for its ability to inhibit Folyl-poly-gamma-glutamyl synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 3.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116253(2-{[3-Carboxy-3-(4-methylamino-benzoylamino)-propy...)
Affinity DataIC50: 5.70E+3nMAssay Description:Compound was evaluated for its ability to inhibit Folyl-poly-gamma-glutamyl synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116251(2-{[3-(4-Amino-benzoylamino)-3-carboxy-propyl]-hyd...)
Affinity DataIC50: 8.60E+3nMAssay Description:Compound was evaluated for its ability to inhibit Folyl-poly-gamma-glutamyl synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50011886(CHEMBL36083 | 5-Amino-2-{4-[(2,4-diamino-pteridin-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory concentration against human Folyl-polyglutamate synthase isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010931(CHEMBL73267 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010928(CHEMBL308279 | 2-{4-[1-(2,4-Diamino-pteridin-6-ylm...)
Affinity DataIC50: 1.18E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054214(2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-amin...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054213(3-(1-Carboxymethyl-1H-imidazol-4-yl)-2-{4-[(2,4-di...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054215(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010924(CHEMBL65616 | 2-{4-[(2,4-Diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010930(CHEMBL307820 | 2-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010929(CHEMBL307486 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051746(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory concentration against human Folyl-polyglutamate synthase isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50018235(CHEMBL38937 | 5-Amino-2-{4-[(2,4-diamino-5-chloro-...)
Affinity DataKi:  1.70nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002472(CHEMBL288142 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  8.30nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002472(CHEMBL288142 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  8.30nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003467(CHEMBL130518 | 5-Amino-2-{4-[(2-amino-4-oxo-5-trif...)
Affinity DataKi:  8.80nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003471(CHEMBL133637 | 5-Amino-2-{4-[(2-amino-4-oxo-5-trif...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50002471(CHEMBL289923 | 5-Amino-2-{4-[(2-amino-4-oxo-2,3,4,...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002471(CHEMBL289923 | 5-Amino-2-{4-[(2-amino-4-oxo-2,3,4,...)
Affinity DataKi:  64nMAssay Description:Potent inhibitor of Folyl-polyglutamate synthase obtained from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006906(CHEMBL23977 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-qui...)
Affinity DataKi:  67nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003470(CHEMBL339240 | 5-Amino-2-{4-[(5-fluoro-2-methyl-4-...)
Affinity DataKi:  150nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011885(CHEMBL280864 | 5-Amino-2-{4-[(2,4-diamino-pteridin...)
Affinity DataKi:  150nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50080450((S)-5-Amino-2-{5-[(2-amino-4-oxo-3,4,5,6,7,8-hexah...)
Affinity DataKi:  200nMAssay Description:Binding affinity as Competitive substrate in the presence of 50 gmM aminopterin towards recombinant Human Folyl-polyglutamate synthase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051747(5-Amino-2-{4-[(2-amino-4-hydroxy-5,6,7,8-tetrahydr...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against mammalian Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50020107(CHEMBL281656 | 5-Amino-2-{4-[(2,4-diamino-pteridin...)
Affinity DataKi:  300nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50020107(CHEMBL281656 | 5-Amino-2-{4-[(2,4-diamino-pteridin...)
Affinity DataKi:  300nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50018236(CHEMBL43288 | 5-Amino-2-[4-(4-oxo-3,4-dihydro-quin...)
Affinity DataKi:  420nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003468(CHEMBL335629 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003469(CHEMBL340993 | 5-Amino-2-{4-[(2-amino-5-fluoro-4-o...)
Affinity DataKi:  900nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50018232(CHEMBL39107 | 5-Amino-2-[4-(4-oxo-3,4-dihydro-quin...)
Affinity DataKi:  1.20E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50020101(CHEMBL281024 | 2-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006907(CHEMBL89641 | 2-{4-[(4-Oxo-3,4-dihydro-quinazolin-...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50006905(CHEMBL316019 | 2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50018234(CHEMBL41161 | 5-Amino-2-[4-(2-amino-4-oxo-3,4-dihy...)
Affinity DataKi:  2.80E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50005868(CHEMBL38902 | 2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hex...)
Affinity DataKi:  3.20E+3nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50020102(CHEMBL28049 | 5-Amino-2-{4-[(2,4-diamino-pteridin-...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50020102(CHEMBL28049 | 5-Amino-2-{4-[(2,4-diamino-pteridin-...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50005859(CHEMBL35921 | 5-Amino-2-{4-[(2,4-diamino-pyrido[3,...)
Affinity DataKi:  5.70E+3nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002473(CHEMBL41743 | 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002473(CHEMBL41743 | 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002473(CHEMBL41743 | 5-Amino-2-{4-[(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity for hog liver Folyl-polyglutamate synthase was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50018233(CHEMBL289372 | 5-Amino-2-[4-(2-amino-4-oxo-3,4-dih...)
Affinity DataKi:  5.90E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50020108(CHEMBL431290 | 5-Amino-2-{4-[(2-amino-4-hydroxy-pt...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from hogMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002472(CHEMBL288142 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  8.30E+3nMAssay Description:Compound was evaluated for its binding affinity against hog liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50020101(CHEMBL281024 | 2-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50005867(CHEMBL40850 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyr...)
Affinity DataKi:  9.00E+3nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50020109(CHEMBL25870 | 2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hex...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from hogMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
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