Compile Data Set for Download or QSAR
Report error Found 1830 Enz. Inhib. hit(s) with Target = 'Galectin-1'
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21519(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-4-(carbam...)
Affinity DataKd:  4.30E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21521(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  4.90E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21522(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  3.40E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21523(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-4-[(butyl...)
Affinity DataKd:  2.30E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21524(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-4-[(dieth...)
Affinity DataKd:  4.60E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21525(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  4.90E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21526(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  2.30E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21527(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  4.50E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21528(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-4-[(benzy...)
Affinity DataKd:  3.50E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21529(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  4.30E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21530(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-4-[(cyclo...)
Affinity DataKd:  4.00E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21531(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-3,5-dihyd...)
Affinity DataKd:  1.60E+5nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21532(N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-4-({[(2S,...)
Affinity DataKd:  5.80E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM21533(N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...)
Affinity DataKd:  7.00E+4nMpH: 7.2 T: 2°CAssay Description:In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120768(US8703720, Reference Compound 1)
Affinity DataKd: >1.00E+7nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120769(US8703720, Reference Compound 2)
Affinity DataKd:  6.50E+4nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120771(US8703720, 15)
Affinity DataKd:  1.90E+3nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120772(US8703720, 16)
Affinity DataKd:  1.50E+3nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120773(US8703720, 17)
Affinity DataKd:  1.20E+3nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120774(US8703720, 18)
Affinity DataKd:  350nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120775(US8703720, 19)
Affinity DataKd:  1.30E+3nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM120776(US8703720, 23)
Affinity DataKd:  6.30E+3nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetGalectin-1 [C3S](Human)
Universit�� De Nantes

LigandPNGBDBM223990(2-[6-Maleimide)caproyl]ethyl [3-O-(2-naphthyl)meth...)
Affinity DataKd:  1.60E+4nMT: 2°CAssay Description:Fluorescence anisotropy was measured on a Tecan infinite M1000 plate reader with an excitation at 470 nm and emission at 525 nm, using Greiner 96 fla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetGalectin-1 [C3S](Human)
Universit�� De Nantes

LigandPNGBDBM223990(2-[6-Maleimide)caproyl]ethyl [3-O-(2-naphthyl)meth...)
Affinity DataKd:  4.30E+4nMT: 2°CAssay Description:Fluorescence anisotropy was measured on a Tecan infinite M1000 plate reader with an excitation at 470 nm and emission at 525 nm, using Greiner 96 fla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetGalectin-1 [C3S](Human)
Universit�� De Nantes

LigandPNGBDBM223991([3-O-(2-naphthyl)methyl-β-D-galactopyranosyl]...)
Affinity DataKd:  2.70E+4nMT: 2°CAssay Description:Fluorescence anisotropy was measured on a Tecan infinite M1000 plate reader with an excitation at 470 nm and emission at 525 nm, using Greiner 96 fla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetGalectin-1 [C3S](Human)
Universit�� De Nantes

LigandPNGBDBM223992(4-O-[3-O-(3-methoxybenzyl)-β-D-galactopyranos...)
Affinity DataKd:  2.30E+4nMT: 2°CAssay Description:Fluorescence anisotropy was measured on a Tecan infinite M1000 plate reader with an excitation at 470 nm and emission at 525 nm, using Greiner 96 fla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetGalectin-1 [C3S](Human)
Universit�� De Nantes

LigandPNGBDBM223993(TD139)
Affinity DataKd:  2.20E+3nMT: 2°CAssay Description:Fluorescence anisotropy was measured on a Tecan infinite M1000 plate reader with an excitation at 470 nm and emission at 525 nm, using Greiner 96 fla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2017
Entry Details Article
PubMed
TargetGalectin-1(Human)
Lund University

LigandPNGBDBM455401(3,3'-Dideoxy-3- [4-(morpholin-4- yl)-1H-1,2,3- tri...)
Affinity DataKd:  110nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM455402(3,3′-Dideoxy-3-[4-(4-methylpiperazin-1-yl)-1...)
Affinity DataKd:  35nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM455403(3,3′-Dideoxy-3-[4-(piperidin-4-yl)-1H-1,2,3-...)
Affinity DataKd:  29nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM455404(3,3′-Dideoxy-3-[4-(tetrahydropyran-4-yl)-1H-...)
Affinity DataKd:  58nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM455405(3,3′-Dideoxy-3-[4-(propan-2-yl)-1H-1,2,3-tri...)
Affinity DataKd:  70nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468287(US10800804, Example S8a | 3′-Deoxy-3-O-[(5,6...)
Affinity DataKd:  320nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468288(US10800804, Example S8b | 3′-Deoxy-3-O-[(5,6...)
Affinity DataKd:  480nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468289(US10800804, Example S8c | 3′-{4-[(Butylamino...)
Affinity DataKd:  1.20E+3nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468290(US10800804, Example S11 | 3-{4-[(Butylamino)carbon...)
Affinity DataKd:  77nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468291(US10800804, Example S16 | 3,3′-Dideoxy-3R...)
Affinity DataKd:  90nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468292(US10800804, Example S20a | 3-(9-anthracene carboxa...)
Affinity DataKd:  380nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468293(US10800804, Example S20b)
Affinity DataKd:  490nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468294(US10800804, Example S21 | 3,3′-Dideoxy-3-[4-...)
Affinity DataKd:  66nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  60nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468296(US10800804, Example 3a | 3,3′-dideoxy-3,3...)
Affinity DataKd:  78nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468297(US10800804, Example 3b)
Affinity DataKd:  79nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468298(US10800804, Example 3c)
Affinity DataKd:  110nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  60nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM478052(US10889610, Example 1 | 4-Bromo-5-cyano- 2-pyridyl...)
Affinity DataKd:  2.60E+3nMAssay Description:The affinity of Example 1-22 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM478059(US10889610, Example 7 | 4-Chloro-2-pyridyl 3-deoxy...)
Affinity DataKd:  6.90E+3nMAssay Description:The affinity of Example 1-22 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM478065(US10889610, Example 12 | 5-Bromo-6-cyano-3-pyridyl...)
Affinity DataKd:  7.00E+3nMAssay Description:The affinity of Example 1-22 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM494606(US10988502, Example 1 | 3,4-Dichlorophenyl 3-deoxy...)
Affinity DataKd:  140nMAssay Description:Compounds for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the interaction between gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetGalectin-1(Human)
Lund University

LigandPNGBDBM494607(US10988502, Example 2 | 2-Chloro-5-fluoro-benzonit...)
Affinity DataKd:  190nMAssay Description:Compounds for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the interaction between gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

Displayed 1 to 50 (of 1830 total ) | Next | Last >>
Jump to: