Compile Data Set for Download or QSAR
Report error Found 1151 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT2'
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622552(CHEMBL5437232)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622549(CHEMBL5403007)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281300(CHEMBL4170225)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281305(CHEMBL4162206)
Affinity DataIC50: 0.5nMAssay Description:Non-competitive inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of 2 to 640 uM SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622551(CHEMBL5424749)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622550(CHEMBL5405913)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281305(CHEMBL4162206)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281305(CHEMBL4162206)
Affinity DataIC50: 0.700nMAssay Description:Competitive inhibition of human G9a using 40 to 2560 nM biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622548(CHEMBL5416767)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446378(CHEMBL3109639)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of G9a (unknown origin) using biotinylated-histone H3(1-21) peptide as substrate after 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446386(CHEMBL3109631)
Affinity DataIC50: 1nMAssay Description:Inhibition of G9a (unknown origin) using biotinylated-histone H3(1-21) peptide as substrate after 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592391(CHEMBL5187766)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50622553(CHEMBL5435285)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50634384(CHEMBL5396581)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant G9a (785 to 1210 residues) expressed in baculovirus-infected Sf9 cells using biotinylated histo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281311(CHEMBL4159604)
Affinity DataIC50: 2nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50353121(CHEMBL1829295)
Affinity DataIC50: 2nMAssay Description:Inhibition of G9a assessed as hydrolysis of S-adenosyl-L-homocysteine after 2 mins by SAHH-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281304(CHEMBL4160008)
Affinity DataIC50: 2nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281304(CHEMBL4160008)
Affinity DataIC50: 2nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50634383(CHEMBL5414343)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant G9a (785 to 1210 residues) expressed in baculovirus-infected Sf9 cells using biotinylated histo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50592384(CHEMBL5195846)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin) using [histone H3 1 to 25 residues] and SAM substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50634385(CHEMBL5433429)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant G9a (785 to 1210 residues) expressed in baculovirus-infected Sf9 cells using biotinylated histo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin) using H3(1-20)-cys as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin) incorporation of tritium-labeled methyl group to biotinylated peptide substrates by Scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of G9a (unknown origin) using histone H3 (1 to 25 residues) as substrate preincubated for 2 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to human recombinant G9a catalytic domain amino acid 913 to 1193 expressed in Escherichia coli BL21 (DE3) by isothermal titration ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50621641(CHEMBL5410162)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human recombinant EHMT2 G9a using SAM as substrate incubated for 1 hr by microplate luminescence based HMT assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281303(CHEMBL4171233)
Affinity DataIC50: 3nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50281296(CHEMBL4173626)
Affinity DataIC50: 3nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50442106(CHEMBL2441078)
Affinity DataIC50: 3nMAssay Description:Inhibition of lysine methyltransferase G9a (unknown origin) using [3H]-SAM as substrate after 0.25 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3nMAssay Description:Inhibition of G9a (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant G9a (785 to 1210 residues) expressed in baculovirus-infected Sf9 cells using biotinylated histo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of G9a (unknown origin) using biotinylated-histone H3(1-21) peptide as substrate after 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50560578(CHEMBL4795328)
Affinity DataIC50: 3.30nMAssay Description:Inhibition G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Displayed 1 to 50 (of 1151 total ) | Next | Last >>
Jump to: