Report error Found 1790 Enz. Inhib. hit(s) with Target = 'Insulin receptor'
Affinity DataKd: 1.20E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 630nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.99E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 1.07E+4nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 1.07E+4nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 520nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 390nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 1.74E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataEC50: 126nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 2.75E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 582nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 241nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 4.17E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 1.32E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 4.58E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 5.03E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 4.76E+3nMAssay Description:Inhibition of insulin stimulated INSR phosphorylation in human HeLa cells preincubated for 1 hr followed by insulin addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 0.0200nMAssay Description:Displacement of [TyrA14-125I]-human insulin from human insulin receptor isoform A expressed in baby hamster kidney cells after 2 days by gamma counti...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at B6D2F1 mouse insulin receptor assessed as increase in glucose incorporation into lipid phase after 2 hrs in presence of D-[3-3H]g...More data for this Ligand-Target Pair
Affinity DataKd: 1.86E+3nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged INSR (unknown origin) (1005 to 1310 residues) expressed in baculovirus inf...More data for this Ligand-Target Pair
Affinity DataKd: 1.69E+3nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged INSR (unknown origin) (1005 to 1310 residues) expressed in baculovirus inf...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at human IR-beta signalling expressed in mouse 3T3 cells assessed as AKT phosphorylation at Ser473 residue after 30 mins by HTRF ass...More data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Binding affinity to human INSR (997 to 1318 residues) expressed in mammalian expression system by kinome scan-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 7.00E+3nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Activation of human insulin receptor tyrosine kinase (IRTK)More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Activation of human IR-B expressed in mouse NIH3T3 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 30 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human InsR expressed in mouse IGF1R knockout MEF cells assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Average Binding Constant for INSR; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 73nMAssay Description:Average Binding Constant for INSR; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
