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Report error Found 659 Enz. Inhib. hit(s) with Target = 'Kallikrein-7'
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612151(CHEMBL5287216)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of KLK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50125021(CHEMBL3623779)
Affinity DataKi:  0.800nMAssay Description:Inhibition of KLK7 (unknown origin) expressed in Pichia pastoris X33 using KHLY-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612150(CHEMBL5281161)
Affinity DataIC50: 1nMAssay Description:Inhibition of KLK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50429202(LYNGBYASTATIN 7)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant kallikrein 7 (23 to 252 residues) using MCA-RPKPVE-Nval-WRK(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Mouse)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)

Curated by ChEMBL
LigandPNGBDBM50598266(CHEMBL5203652)
Affinity DataKi:  4.10nMAssay Description:Inhibition of mouse KLK7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant kallikrein 7 (23 to 252 residues) using MCA-RPKPVE-Nval-WRK(Dnp)-NH2 as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598311(CHEMBL5185665)
Affinity DataKi:  7nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598297(CHEMBL5198206)
Affinity DataKi:  8.80nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598292(CHEMBL5173572)
Affinity DataKi:  9nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598306(CHEMBL5173148)
Affinity DataKi:  10nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598296(CHEMBL5179139)
Affinity DataKi:  12nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598309(CHEMBL5204039)
Affinity DataKi:  16nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50124906(CHEMBL3623776)
Affinity DataKi:  17nMAssay Description:Inhibition of KLK7 (unknown origin) expressed in Pichia pastoris X33 using KHLY-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598301(CHEMBL5189873)
Affinity DataKi:  18nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598305(CHEMBL5191378)
Affinity DataKi:  19nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598310(CHEMBL5185516)
Affinity DataKi:  29nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598295(CHEMBL5175658)
Affinity DataKi:  29nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598288(CHEMBL5204199)
Affinity DataKi:  31nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598291(CHEMBL5177855)
Affinity DataKi:  32nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598307(CHEMBL5177530)
Affinity DataKi:  36nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM336124(US9744148, 1)
Affinity DataIC50: 39nMAssay Description:Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM32709(1-(4-methylbenzoyl)-3-(3-pyridinyl)-1H-1,2,4-triaz...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113060(US9695194, 1)
Affinity DataKi:  48nM ΔG°:  -43.5kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50460879(CHEMBL4228441)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113069(US9695194, 5)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human KLK7 using S-2586 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598303(CHEMBL5180009)
Affinity DataKi:  50nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598302(CHEMBL5191079)
Affinity DataKi:  52nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598300(CHEMBL5177117)
Affinity DataKi:  53nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50275974(CHEMBL4126936)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50275974(CHEMBL4126936)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113283(US9695194, 8)
Affinity DataKi:  65nM ΔG°:  -42.7kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598290(CHEMBL5175954)
Affinity DataKi:  66nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50266979(CHEMBL4061897)
Affinity DataKi:  69nMAssay Description:Inhibition of recombinant KLK7 (unknown origin) expressed in zymogen form in Pichia pastorisstrain X-33 using KHLY-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM336128(US9744148, 2)
Affinity DataIC50: 70nMAssay Description:Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113065(US9695194, 2)
Affinity DataKi:  73nM ΔG°:  -42.4kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113119(US9695194, 6)
Affinity DataKi:  80nM ΔG°:  -42.1kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM336129(US9744148, 3)
Affinity DataIC50: 80nMAssay Description:Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM336130(US9744148, 4)
Affinity DataIC50: 80nMAssay Description:Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113069(US9695194, 5)
Affinity DataKi:  85nM ΔG°:  -42.0kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598308(CHEMBL5192988)
Affinity DataKi:  90nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM336132(US9744148, 5)
Affinity DataIC50: 90nMAssay Description:Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113248(US9695194, 7)
Affinity DataKi:  90nM ΔG°:  -41.8kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598289(CHEMBL5190884)
Affinity DataKi:  94nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598293(CHEMBL5172075)
Affinity DataKi:  96nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50289001(2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazi...)
Affinity DataKi:  100nM ΔG°:  -41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113299(US9695194, 15)
Affinity DataKi:  105nM ΔG°:  -41.4kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50598287(CHEMBL5183937)
Affinity DataKi:  106nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK7 (30 to 253 residues) transfected in CHO cells assessed as inhibition constant using K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50460884(CHEMBL4228178)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM113067(US9695194, 3)
Affinity DataKi:  116nM ΔG°:  -41.2kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetKallikrein-7(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM336133(US9744148, 6)
Affinity DataIC50: 120nMAssay Description:Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

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