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Report error Found 132 Enz. Inhib. hit(s) with Target = 'Malate dehydrogenase, cytoplasmic'
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250242BDBM50250242(CHEMBL4068781 | US12630497, Compound 9-2)
Affinity DataKi:  740nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250223BDBM50250223(CHEMBL4096306 | US12630497, Compound 3-17)
Affinity DataIC50: 920nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250242BDBM50250242(CHEMBL4068781 | US12630497, Compound 9-2)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400094BDBM50400094(CHEMBL427092 | US12630497, Compound 3-20)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MDH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250235BDBM50250235(CHEMBL4065526 | US12630497, Compound 3-12)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250244BDBM50250244(CHEMBL4091027 | US12630497, Compound 3-33)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250220BDBM50250220(CHEMBL4098767 | US12630497, Compound 3-29)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250243BDBM50250243(CHEMBL4074947 | US12630497, Compound 3-30)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250218BDBM50250218(CHEMBL4074694 | US12630497, Compound 9-3)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250231BDBM50250231(CHEMBL4068233 | US12630497, Compound 3-24)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250230BDBM50250230(CHEMBL4087903 | US12630497, Compound 3-27)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250226BDBM50250226(CHEMBL4099949 | US12630497, Compound 3-14)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400094BDBM50400094(CHEMBL427092 | US12630497, Compound 3-20)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400092BDBM50400092(CHEMBL2178409 | US12630497, Compound 6-2)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250231BDBM50250231(CHEMBL4068233 | US12630497, Compound 3-24)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250226BDBM50250226(CHEMBL4099949 | US12630497, Compound 3-14)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250243BDBM50250243(CHEMBL4074947 | US12630497, Compound 3-30)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250242BDBM50250242(CHEMBL4068781 | US12630497, Compound 9-2)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250227BDBM50250227(CHEMBL4073085 | US12630497, Compound 3-13)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250220BDBM50250220(CHEMBL4098767 | US12630497, Compound 3-29)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400097BDBM50400097(CHEMBL2177118 | US12630497, Compound 9-1)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250235BDBM50250235(CHEMBL4065526 | US12630497, Compound 3-12)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808071BDBM808071(Methyl 4-(4-methoxybenzyloxy)-3-(2-(4-(2,4,4-trime...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808087BDBM808087((E)-methyl 4-hydroxy-3-(3-(4-(2,4,4-trimethylpenta...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250230BDBM50250230(CHEMBL4087903 | US12630497, Compound 3-27)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250223BDBM50250223(CHEMBL4096306 | US12630497, Compound 3-17)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250244BDBM50250244(CHEMBL4091027 | US12630497, Compound 3-33)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400096BDBM50400096(CHEMBL2178406 | US12630497, Compound 3-32)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250219BDBM50250219(CHEMBL4095380 | US12630497, Compound 3-31)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250245BDBM50250245(CHEMBL4086789 | US12630497, Compound 3-15)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250219BDBM50250219(CHEMBL4095380 | US12630497, Compound 3-31)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250218BDBM50250218(CHEMBL4074694 | US12630497, Compound 9-3)
Affinity DataIC50: 3.00E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250227BDBM50250227(CHEMBL4073085 | US12630497, Compound 3-13)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250245BDBM50250245(CHEMBL4086789 | US12630497, Compound 3-15)
Affinity DataIC50: 4.74E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 23227BDBM23227([(4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]car...)
Affinity DataIC50: 4.88E+3nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250221BDBM50250221(CHEMBL4080721 | US12630497, Compound 3-34)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 23223BDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 5.80E+3nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Pig)
University of Mississippi

LigandChemical structure of BindingDB Monomer ID 23229BDBM23229([(4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]car...)
Affinity DataIC50: 6.31E+3nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250236BDBM50250236(CHEMBL4105436 | US12630497, Compound 3-11)
Affinity DataIC50: 6.65E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23229BDBM23229([(4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]car...)
Affinity DataIC50: 6.78E+3nMAssay Description:Inhibition of human recombinant carboxy-terminal his-tagged MDH-1 (3 to 334) expressed in Escherichia coli using oxaloacetic acid as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250238BDBM50250238(CHEMBL4085170 | US12630497, Compound 3-8)
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808080BDBM808080((E)-methyl 4-methyl-3-(3-(4-(2,4,4-trimethylpentan...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808095BDBM808095(Methyl 5-(3-(4-(2,4,4-trimethylpentan-2-yl)phenoxy...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250236BDBM50250236(CHEMBL4105436 | US12630497, Compound 3-11)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250221BDBM50250221(CHEMBL4080721 | US12630497, Compound 3-34)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808085BDBM808085((E)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl 3-(4-(2,...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808084BDBM808084((E)-methyl 2,4-dimethyl-5-(3-(4-(2,4,4-trimethylpe...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250238BDBM50250238(CHEMBL4085170 | US12630497, Compound 3-8)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 808091BDBM808091(Methyl 4-methyl-3-(3-(4-(2,4,4-trimethylpentan-2-y...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250248BDBM50250248(CHEMBL4078740 | US12630497, Compound 3-7)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

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