Compile Data Set for Download or QSAR
Report error Found 1956 Enz. Inhib. hit(s) with Target = 'Melatonin receptor type 1A'
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263702(CHEMBL4092308)
Affinity DataEC50: >1.00E+4nMAssay Description:Intrinsic activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263727(CHEMBL4064626)
Affinity DataEC50: >1.00E+4nMAssay Description:Intrinsic activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263691(CHEMBL4064813)
Affinity DataEC50:  20nMAssay Description:Intrinsic activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50263729(CHEMBL4074273)
Affinity DataEC50: >1.00E+4nMAssay Description:Intrinsic activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464402(CHEMBL4279639)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464401(CHEMBL4288690)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464410(CHEMBL4292109)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464400(CHEMBL4293386)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464412(CHEMBL4278248)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464407(CHEMBL4292336)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464406(CHEMBL4280601)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464404(CHEMBL4286494)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464420(CHEMBL4290302)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464421(CHEMBL4286896)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464403(CHEMBL4294790)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464399(CHEMBL4278446)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464416(CHEMBL4289115)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464417(CHEMBL4280791)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464422(CHEMBL4277390)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464418(CHEMBL4284223)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464405(CHEMBL4281915)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464409(CHEMBL4283539)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464413(CHEMBL4281712)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464402(CHEMBL4279639)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464411(CHEMBL4291381)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464405(CHEMBL4281915)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50464415(CHEMBL4278575)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50468601(CHEMBL4285498)
Affinity DataEC50:  3.97E+5nMAssay Description:Agonist activity at human MT1 receptor expressed in HEK293 cells after 24 hrs by Fluo-8 dye-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230660(CHEMBL290646)
Affinity DataKd:  160nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469989(CHEMBL419024)
Affinity DataKd:  190nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037253(2-Iodo-N-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-aceta...)
Affinity DataKd:  0.520nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230659(CHEMBL37549)
Affinity DataKd:  0.000453nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469990(CHEMBL111063)
Affinity DataKd:  20nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037247(Cyclopropanecarboxylic acid [2-(5-methoxy-benzofur...)
Affinity DataKd:  4.10nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469992(CHEMBL108762)
Affinity DataKd:  71nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469991(CHEMBL109784)
Affinity DataKd:  65nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037219(N-[2-(5-Methoxy-benzo[b]thiophen-3-yl)-ethyl]-acet...)
Affinity DataKd:  0.560nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50408555(CHEMBL322762)
Affinity DataKd:  0.201nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037234(1H-Indole-2-carboxylic acid [2-(7-methoxy-naphthal...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50408649(CHEMBL37703)
Affinity DataKd:  2.30nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037245(Heptanoic acid [2-(7-methoxy-naphthalen-1-yl)-ethy...)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469994(CHEMBL111062)
Affinity DataKd:  170nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469995(CHEMBL324078)
Affinity DataKd:  120nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230661(CHEMBL288301)
Affinity DataKd:  24nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50230663(CHEMBL34349)
Affinity DataKd:  0.00343nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50469996(CHEMBL111673)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50408556(CHEMBL37771)
Affinity DataKd:  0.0219nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037220(1-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-pyrrolidin...)
Affinity DataKd:  53nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
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