Compile Data Set for Download or QSAR
Report error Found 371 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 8'
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293721(cid_44191096 | CHEMBL562551 | N-(4-chloro-3-methox...)
Affinity DataEC50:  6.17E+3nMAssay Description:Assigned Assay Grant Number: NS053536-01 Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.35E+4nMAssay Description:Assigned Assay Grant Number: NS053536-01 Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM82006(D-AP4 | D-APB | US9212196, L-AP4)
Affinity DataEC50:  290nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  2.92E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196907(US9212196, Derivative 3)
Affinity DataEC50:  1.84E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196908(US9212196, Derivative 4)
Affinity DataEC50:  2.72E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196909(US9212196, Derivative 5)
Affinity DataEC50:  3.72E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196910(US9212196, Derivative 6)
Affinity DataEC50:  1.03E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196911(US9212196, Derivative 7)
Affinity DataEC50:  4.40E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196912(US9212196, Derivative 8)
Affinity DataEC50:  2.80E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196913(US9212196, Derivative 9)
Affinity DataEC50:  1.09E+5nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196914(US9212196, Derivative 10)
Affinity DataEC50:  2.19E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196915(US9212196, Derivative 11)
Affinity DataEC50:  4.90E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196916(US9212196, Derivative 12)
Affinity DataEC50:  4.87E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196917(US9212196, Derivative 13)
Affinity DataEC50:  2.80E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196918(US9212196, Derivative 14)
Affinity DataEC50:  1.12E+5nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196919(US9212196, Derivative 15)
Affinity DataEC50:  7.10E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196920(US9212196, Derivative 16 | US9212196, Derivative 1...)
Affinity DataEC50:  3.60E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196920(US9212196, Derivative 16 | US9212196, Derivative 1...)
Affinity DataEC50:  2.93E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196922(US9212196, Derivative 18)
Affinity DataEC50:  1.41E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196923(US9212196, Derivative 19)
Affinity DataEC50:  2.50E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196924(US9212196, Derivative 20)
Affinity DataEC50:  5.56E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196925(US9212196, Derivative 21)
Affinity DataEC50:  6.86E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196926(US9212196, Derivative 22)
Affinity DataEC50:  3.40E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196927(US9212196, Derivative 23)
Affinity DataEC50:  7.40E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196928(US9212196, Derivative 24)
Affinity DataEC50:  1.59E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196929(US9212196, Derivative 25)
Affinity DataEC50:  1.15E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196930(US9212196, Derivative 26)
Affinity DataEC50:  1.23E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196932(US9212196, Derivative 28)
Affinity DataEC50:  2.75E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196933(US9212196, Derivative 29)
Affinity DataEC50:  1.43E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196934(US9212196, Derivative 30)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196935(US9212196, Derivative 31)
Affinity DataEC50: >3.00E+5nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196936(US9212196, Derivative 32)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196937(US9212196, Derivative 33)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196938(US9212196, Derivative 34)
Affinity DataEC50:  9.17E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM196939(US9212196, Derivative 35)
Affinity DataEC50:  3.82E+4nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244219(CHEMBL4081453)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu8 receptor expressed in hamster AV12 cells co-expressing rat EAAT1/Galpha15 assessed as induction of increa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255294(CHEMBL4090312)
Affinity DataEC50:  8.40E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255291(CHEMBL4060017)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255338(CHEMBL4083240)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255336(CHEMBL4064187)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255406(CHEMBL4088782)
Affinity DataEC50:  490nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255333(CHEMBL4082270)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255403(CHEMBL4101241)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255341(CHEMBL4075070)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255334(CHEMBL4094241)
Affinity DataEC50:  5.40E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255370(CHEMBL4079075)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255293(CHEMBL4094636)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
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