Compile Data Set for Download or QSAR
Report error Found 4759 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7'
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397111(US9987259, Example 1 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397112(US9987259, Example 2 | N-[(3R)-1-azabicyclo[2.2.2]...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397113(US9987259, Example 3 | N-[(3S)-1-azabicyclo[2.2.2]...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397114(US9987259, Example 6 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397115(US9987259, Example 7 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397116(US9987259, Example 9 | N-(1-azabicyclo[2.2.2]octan...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397117(US9987259, Example 10 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397118(US9987259, Example 11 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397119(US9987259, Example 12 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  750nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397120(US9987259, Example 13 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397121(US9987259, Example 14 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397122(US9987259, Example 15 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397123(US9987259, Example 16 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397124(US9987259, Example 17 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397125(US9987259, Example 18 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397126(US9987259, Example 19 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397127(US9987259, Example 20 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397128(US9987259, Example 21 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397129(US9987259, Example 22 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  750nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397130(US9987259, Example 23 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397131(US9987259, Example 24 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397132(US9987259, Example 25 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  750nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397133(US9987259, Example 26 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397134(US9987259, Example 27 | N-[(3R)-1-azabicyclo[2.2.2...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397135(US9987259, Example 28 | N-[(3S)-1-azabicyclo[2.2.2...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397136(US9987259, Example 29 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397137(US9987259, Example 30 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397138(US9987259, Example 33 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397139(US9987259, Example 42 | N-(1-azabicyclo[2.2.2]octa...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397140(US9987259, Example 45 | (1-azabicyclo[2.2.2]octan-...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397141(US9987259, Example 46 | US10456385, Example 46)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM50143314(CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyrid...)
Affinity DataEC50:  28nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2012
Entry Details

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  740nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2012
Entry Details

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91593(DMXB-A)
Affinity DataEC50:  2.40E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2012
Entry Details

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91594(Tropisetron)
Affinity DataEC50:  92nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2012
Entry Details

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM50161764(CHEMBL177611 | (R)-4-chloro-N-(quinuclidin-3-yl)be...)
Affinity DataEC50:  40nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2012
Entry Details

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM50190786(CHEMBL214268 | PHA-543613 | N-[(3R)-1-azabicyclo[2...)
Affinity DataEC50:  4.20nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2012
Entry Details

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91595(PHA568487)
Affinity DataEC50:  35nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2012
Entry Details

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91596(alpha7 agonists 1)
Affinity DataEC50:  3.70E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91707(alpha7 agonists 1')
Affinity DataEC50:  6.00E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91598(alpha7 agonists 2)
Affinity DataEC50:  1.20E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91599(2' | alpha7 agonists 2')
Affinity DataEC50:  4.20E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91600(alpha7 agonists 3)
Affinity DataEC50:  1.80E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91601(3' | alpha7 agonists 3')
Affinity DataEC50:  2.90E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91602(alpha7 agonists 4)
Affinity DataEC50:  300nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91603(4' | alpha7 agonists 4')
Affinity DataEC50:  600nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91604(alpha7 agonists 5)
Affinity DataEC50:  800nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91605(5' | alpha7 agonists 5')
Affinity DataEC50:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91606(alpha7 agonists 6)
Affinity DataEC50:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM91607(alpha7 agonists 7)
Affinity DataEC50:  900nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 l of 0.2 mg/ml ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2012
Entry Details Article
PubMed
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