Report error Found 3259 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor delta'
Affinity DataKi: 0.00483nMAssay Description:Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARdelta LBD by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0102nMAssay Description:Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARdelta LBD by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0480nMAssay Description:Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARdelta LBD by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0600nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 0.100nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 0.100nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARdelta LBD by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at human PPARbeta expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 0.300nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)More data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human PPARdelta transfected in african green monkey COS7 cells assessed transactivation incubated for 16 hrs by luciferase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARdelta LBD by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at pSG5-Gal4-tagged human PPAR-beta/delta ligand binding domain expressed in COS1 cells assessed as receptor activation incubated fo...More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at Gal4-fused human PPARdelta DNA binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 0.580nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Agonist activity at human PPARdelta transfected in african green monkey COS7 cells assessed transactivation incubated for 16 hrs by luciferase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM EC50: 2.00E+3nMAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARdelta LBD by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Transactivation of human PPARdelta expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Transactivation of GAL4-fused human PPARdelta expressed in African green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.720nMAssay Description:Agonist activity at PPARdelta receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.720nMAssay Description:Transactivation of Gal4-fused human PPARdelta expressed in HEK293 cells after 16 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at human PPARdelta transfected in african green monkey COS7 cells assessed transactivation incubated for 16 hrs by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 0.820nMAssay Description:Binding affinity to PPARdelta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.910nMAssay Description:Effect on PPARdelta transactivation activity in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.950nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at PPAR delta (unknown origin) transfected in HEK293 cells after 24 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPAR-delta assessed as receptor transactivation by measuring maximum induction of alkaline phosphatase activityMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity for human PPAR delta receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Maximum transcriptional activation of human PPAR delta receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
