Compile Data Set for Download or QSAR
Report error Found 284 Enz. Inhib. hit(s) with Target = 'Pituitary adenylate cyclase-activating polypeptide'
LigandPNGBDBM50550811(CHEMBL4740931)
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50606527(CHEMBL5220770)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at PAC1R in human SH-SY5Y cells assessed as cAMP accumulation incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50250068(PACAP(1-27) | PACAP-27 | CHEMBL501240 | [Glu3]PACA...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2011
Entry Details Article
PubMed
LigandPNGBDBM50250019(PACAP | PACAP-38 | CHEMBL524658 | PACAP(1-38) | PA...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2011
Entry Details Article
PubMed
LigandPNGBDBM50596676(CHEMBL5203375)
Affinity DataIC50: 0.110nMAssay Description:Antagonist activity at PAC-1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced increase in intracellular cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50200209(CHEMBL219499)
Affinity DataEC50:  0.130nMAssay Description:Activity at human PAC1 receptor in CHO cells by measuring cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50550810(CHEMBL4757203)
Affinity DataIC50: 0.182nMAssay Description:Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50250019(PACAP | PACAP-38 | CHEMBL524658 | PACAP(1-38) | PA...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM82448([Ala2]PACAP(1-27))
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM50250023(CHEMBL500280 | [Ala2]PACAP(1-38) | [Ala2]PACAP38)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM50250081([Hyp2]PACAP38 | CHEMBL499507)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM82447([DAla2]PACAP(1-38))
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM50250076([Nal6]PACAP27 | CHEMBL525613)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250033([Ala7]PACAP38 | CHEMBL525419)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250074([Bip6]PACAP27 | CHEMBL507480)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM82450([AcHis1]PACAP(1-27))
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM50250075([Bip6]PACAP38 | CHEMBL526315)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250077([Nal6]PACAP38 | CHEMBL503123)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM81535(CHEMBL525267 | PACAP(6-38))
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details Article
PubMed
LigandPNGBDBM50596675(CHEMBL5208587)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at PAC-1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced increase in intracellular cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM81535(CHEMBL525267 | PACAP(6-38))
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2011
Entry Details Article
PubMed
LigandPNGBDBM50250069([Glu3]PACAP38 | CHEMBL524494)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250019(PACAP | PACAP-38 | CHEMBL524658 | PACAP(1-38) | PA...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
LigandPNGBDBM81535(CHEMBL525267 | PACAP(6-38))
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM81524([Phe2]PACAP(1-38))
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM50250019(PACAP | PACAP-38 | CHEMBL524658 | PACAP(1-38) | PA...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250080([Hyp2]PACAP27 | CHEMBL524495)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at PAC1R in human SH-SY5Y cells assessed as cAMP accumulation incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50250061([His(1-Me)1]PACAP38 | CHEMBL498948)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250071([Cha6]PACAP38 | CHEMBL524683)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250073([Tyr6]PACAP38 | CHEMBL526360)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250035([D-His1]PACAP38 | CHEMBL525073)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM82440(PACAP(6-31))
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM50200209(CHEMBL219499)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]PACAP27 from human PAC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM82356(PACAP(2-38))
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
LigandPNGBDBM81825(PACAP(1-23),VIP(24-28))
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50250087([Aib4]PACAP38 | CHEMBL499665)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50606528(CHEMBL5219662)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at PAC1R in human SH-SY5Y cells assessed as inhibition of PACAP38-induced cAMP accumulation pre-incubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50250033([Ala7]PACAP38 | CHEMBL525419)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250037([D-Ser2]PACAP38 | CHEMBL524894)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250079([Pro2]PACAP38 | CHEMBL506840)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250085([Aib2]PACAP38 | CHEMBL506517)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250059(Ac-PACAP38 | CHEMBL530563)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250074([Bip6]PACAP27 | CHEMBL507480)
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50250018(PACAP27 | CHEMBL524852)
Affinity DataIC50: 4.60nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human PAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50250068(PACAP(1-27) | PACAP-27 | CHEMBL501240 | [Glu3]PACA...)
Affinity DataKi:  4.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50250034([D-His1]PACAP27 | CHEMBL499781)
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM81534(PACAP(4-38))
In Depth
Date in BDB:
9/28/2011
Entry Details Article
PubMed
LigandPNGBDBM81531([D-Phe2]PACAP-38 | [DPhe2]PACAP(1-38))
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
LigandPNGBDBM81536(PACAP(5-38))
In Depth
Date in BDB:
11/9/2011
Entry Details Article
PubMed
Displayed 1 to 50 (of 284 total ) | Next | Last >>
Jump to: