Report error Found 6356 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha/beta'
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 2.74E+4nMAssay Description:Binding affinity to NT-647 labelled recombinant HSP90 (unknown origin) C-terminal domain assessed as dissociation constant by microscale thermophores...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 1.60nMAssay Description:Binding affinity to human PDE4 assessed as dissociation constantMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 0.260nMAssay Description:Binding affinity to human PDE4 assessed as dissociation constantMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Inhibition of full-length Nurr1-RXRalpha in human SH-SY5Y cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: <1nMAssay Description:Inhibition of human full length Nurr1-RXRalpha transfected in COS7 cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Binding affinity to human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system/CyclinD3 by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 440nMAssay Description:Binding affinity to human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system/CyclinD3 by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system/CyclinD3 by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 3.00E+3nMAssay Description:Binding affinity to human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system/CyclinD3 by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 910nMAssay Description:Binding affinity to human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system/CyclinD3 by KdELECT kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 2.11E+4nMAssay Description:Binding affinity to HSP90 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 0.720nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 0.410nMAssay Description:Inhibition of human PD-1 expressed in rat PBMCs/human PD-L1 expressed in MDA-MB-231 cells protein-protein interaction assessed as increase in PBMCs p...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 6.00E+4nMAssay Description:Stabilization of 14-3-3 eta (unknown origin)/ c-Raf (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataKd: 82nMAssay Description:Binding affinity to PRC2 complex of EZH2-EED-SUZ12 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 90nMAssay Description:Activation of caspase 3/7 in human 22Rv1 cells by Caspase-Glo reagent based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Activation of caspase 3/7 in human 22Rv1 cells by Caspase-Glo reagent based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Activation of caspase 3/7 in human 22Rv1 cells by Caspase-Glo reagent based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 412nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 610nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 125nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 430nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 94nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 873nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 138nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 208nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 44nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 2.80E+4nMAssay Description:Modulation of rat alpha6beta3gamma2 GABA A receptor expressed in Xenopus oocytes assessed as reduction in desensitization at -80 mV holding potential...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 3.80E+4nMAssay Description:Modulation of rat alpha6beta3gamma2 GABA A receptor expressed in Xenopus oocytes assessed as reduction in desensitization at -80 mV holding potential...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 3.80E+4nMAssay Description:Modulation of rat alpha6beta3gamma2 GABA A receptor expressed in Xenopus oocytes assessed as reduction in desensitization at -80 mV holding potential...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 9.80E+4nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 3.60E+5nMAssay Description:Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 1.80E+4nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 1.30E+4nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 9.00E+3nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 1.60E+5nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-i...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-i...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 23nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 28nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 8nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame
Curated by ChEMBL
University of Notre Dame
Curated by ChEMBL
Affinity DataEC50: 2.40E+4nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair










































