Compile Data Set for Download or QSAR
Report error Found 385 Enz. Inhib. hit(s) with Target = 'Probable G-protein coupled receptor 139'
LigandPNGBDBM263368((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...)
Affinity DataEC50:  61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743214(Preparation of (S)—N-(1-(4-fluorophenyl)ethyl-2-(4...)
Affinity DataEC50:  56nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743215(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743216(Preparation of (S)—N-(1-(4-methoxyphenyl)ethyl)-2-...)
Affinity DataEC50:  60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743217(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  111nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743218(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  25nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743219(Preparation of (S)—N-1-(4-chlorophenyl)ethyl-2-(4-...)
Affinity DataEC50:  30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743220(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  45nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743221(Preparation of (S)—N-(1-(4-fluorophenyl)ethyl-2-(6...)
Affinity DataEC50:  19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743222(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743223(Preparation of (S)—N-(1-(4-methoxyphenyl)ethyl-2-(...)
Affinity DataEC50:  24nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743224(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743225(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743226(Preparation of (S)—N-1-(4-chlorophenyl)ethyl-2-(6-...)
Affinity DataEC50:  23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743227(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  95nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743228(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  93nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743229(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  34nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743230(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743231(Preparation of (S)-2-(6,8-dimethyl-4-oxopyrrolo[1,...)
Affinity DataEC50:  96nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743232(Preparation of (S)—N-1-(4-chlorophenyl)ethyl-2-(6,...)
Affinity DataEC50:  56nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743233(Preparation of (S)—N-(1-(naphthalen-1-ethyl)-2-(4-...)
Affinity DataEC50:  23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743234(Preparation of (S)—N-(1-(4-bromophenyl)ethyl-2-(4-...)
Affinity DataEC50:  33nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743235(Preparation of (S)-2-(6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  42nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743236(Preparation of (S)—N-1-(4-bromophenyl)ethyl-2-(6-m...)
Affinity DataEC50:  15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743237(Preparation of (S)-2-(4-oxopyrrolo[1,2-d][1,2,4]tr...)
Affinity DataEC50:  61nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743238(Preparation of (S)—N-(2-methyl-1-phenylpropyl)-2-(...)
Affinity DataEC50:  57nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743239(Preparation of (S)—N-(1-(4-fluorophenyl)-2-methylp...)
Affinity DataEC50:  120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743240(Preparation of (S)—N-(2-methyl-1-(4-trifluoromethy...)
Affinity DataEC50:  61nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743241(Preparation of (S)—N-(1-(4-fluorophenyl)-2-methylp...)
Affinity DataEC50:  26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743242(Preparation of (S)—N-(2-methyl-1-(4-trifluoromethy...)
Affinity DataEC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743243(Preparation of (S)-2 (6-methyl-4-oxopyrrolo[1,2-d]...)
Affinity DataEC50:  22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM743244(US20250163065, Compound I-46)
Affinity DataEC50:  68nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM263505(n-(4-chlorophenethyl)-2-(4-oxobenzo[d][1,2,3]triaz...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566727(CHEMBL1310918)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566728(CHEMBL4866435)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM263506(n-(3-chlorophenethyl)-2-(4-oxobenzo[d][1,2,3]triaz...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566729(CHEMBL1380104)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM263507(n-(4-methylphenethyl)-2-(4-oxobenzo[d][1,2,3]triaz...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566730(CHEMBL4869485)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM263508((r)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(2-...)
Affinity DataEC50:  288nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566731(CHEMBL4856162)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM263510((s)-n-(1-(4-methoxyphenyl)propan-2-yl)-2-(4-oxoben...)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566732(CHEMBL4852809)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566733(CHEMBL4878791)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566734(CHEMBL1546963)
Affinity DataEC50:  293nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566735(CHEMBL4860510)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM263391((s)-n-(1-(4-chlorophenyl)ethyl)-2-(4-oxobenzo[d][1...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM263433((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566736(CHEMBL4874254)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM263370((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
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