Compile Data Set for Download or QSAR
Report error Found 302 Enz. Inhib. hit(s) with Target = 'Protein polybromo-1'
TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591346(CHEMBL5188924 | US20240190828, Compound 5)
Affinity DataKd:  1.84E+4nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [676-746](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591346(CHEMBL5188924 | US20240190828, Compound 5)
Affinity DataKd:  1.79E+5nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50184981(CHEMBL3823055 | US20240190828, Compound 7)
Affinity DataKd:  690nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [676-746](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50184981(CHEMBL3823055 | US20240190828, Compound 7)
Affinity DataKd:  350nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591357(CHEMBL5205514 | US20240190828, Compound 8)
Affinity DataKd:  6.89E+3nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [676-746](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591357(CHEMBL5205514 | US20240190828, Compound 8)
Affinity DataKd:  3.26E+3nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591358(CHEMBL5204703 | US20240190828, Compound 11)
Affinity DataKd:  9.30E+3nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [676-746](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591358(CHEMBL5204703 | US20240190828, Compound 11)
Affinity DataKd:  1.01E+4nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591363(CHEMBL5170275 | US20240190828, Compound 16)
Affinity DataKd:  1.48E+3nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [676-746](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591363(CHEMBL5170275 | US20240190828, Compound 16)
Affinity DataKd:  3.94E+3nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataKd:  4.39E+3nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [676-746](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataKd:  2.47E+4nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591346(CHEMBL5188924 | US20240190828, Compound 5)
Affinity DataKd:  4.53E+4nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591347(CHEMBL541514 | US20240190828, Compound 6)
Affinity DataKd:  7.90E+4nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591348(CHEMBL5175984 | US20240190828, Compound 6a)
Affinity DataKd:  1.70E+5nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591349(CHEMBL5178477 | US20240190828, Compound 6b)
Affinity DataKd:  9.02E+5nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591350(CHEMBL5185745 | US20240190828, Compound 6c)
Affinity DataKd:  7.09E+5nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50460600(CHEMBL118266 | US20240190828, Compound 6d)
Affinity DataKd:  1.39E+6nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591351(CHEMBL553944 | US20240190828, Compound 6e)
Affinity DataKd:  1.20E+6nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591352(CHEMBL5178125 | US20240190828, Compound 6f)
Affinity DataKd:  1.45E+6nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591353(CHEMBL1320567 | US20240190828, Compound 6g)
Affinity DataKd:  1.21E+6nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591354(CHEMBL5201008 | US20240190828, Compound 6h)
Affinity DataKd: >2.00E+6nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591355(CHEMBL5177017 | US20240190828, Compound 6i)
Affinity DataKd: >2.00E+6nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591356(CHEMBL5208969 | US20240190828, Compound 6j)
Affinity DataKd: >2.00E+6nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PBRM1 bromodomain-2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PBRM1 bromodamian-5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to human PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 1 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd:  8.10E+3nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged PBRM1 BD1 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged PBRM1 BD5 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM249277(US9458145, 1020-18 | US10017501, Compound 1020-18)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 1 (S178 to E291 residues) expressed in bacterial expression system after 1 hr by bromoscan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM249277(US9458145, 1020-18 | US10017501, Compound 1020-18)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system after 1 hr by bromoscan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50266286(CHEMBL4650213)
Affinity DataKd:  48nMAssay Description:Reverse ITC (compound as receptor). Domain start/stop: S613-D734More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataKd:  1.42E+4nMAssay Description:Reverse ITC (compound as receptor). Domain start/stop: S613-D734More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50549126(CHEMBL4793170)
Affinity DataKd:  64nMAssay Description:Binding affinity to polybromo-1 (5) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50549127(CHEMBL4790365)
Affinity DataKd:  238nMAssay Description:Binding affinity to polybromo-1 (5) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM394406(US10308614, Example 7 | 2-(6-amino-5-(piperazin-)
Affinity DataKd:  26nMAssay Description:Binding affinity to polybromo-1 (5) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM394399(US10308614, Example 1 | tert-butyl 4-(3-amino-6-(2...)
Affinity DataKd:  13nMAssay Description:Binding affinity to polybromo-1 (5) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50549126(CHEMBL4793170)
Affinity DataKd:  4.16E+3nMAssay Description:Binding affinity to polybromo-1 (4) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50549127(CHEMBL4790365)
Affinity DataKd:  3.11E+3nMAssay Description:Binding affinity to polybromo-1 (4) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50549128(CHEMBL4753080)
Affinity DataKd:  2.94E+3nMAssay Description:Binding affinity to polybromo-1 (4) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM394399(US10308614, Example 1 | tert-butyl 4-(3-amino-6-(2...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to polybromo-1 (4) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50549129(CHEMBL4788561)
Affinity DataKd:  840nMAssay Description:Binding affinity to polybromo-1 (3) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50549126(CHEMBL4793170)
Affinity DataKd:  448nMAssay Description:Binding affinity to polybromo-1 (3) (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
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