Report error Found 59 Enz. Inhib. hit(s) with Target = 'Pyruvate kinase PKLR'
Affinity DataEC50: 10.3nMAssay Description:Human PKLR was diluted into Assay Buffer to a final concentration of 5 pM. Enzyme-Assay Buffer mix was dispensed into 384-well shallow-well white-wal...More data for this Ligand-Target Pair
Affinity DataKd: 3.60E+7nMAssay Description:Binding affinity to Sprague-Dawley rat pyruvate kinase L assessed as apprent enzyme-inhibitor dissociation constant using PEP as substrate by spectro...More data for this Ligand-Target Pair
Affinity DataEC50: 32.1nMAssay Description:Human PKLR was diluted into Assay Buffer to a final concentration of 5 pM. Enzyme-Assay Buffer mix was dispensed into 384-well shallow-well white-wal...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 1.39E+3nMAssay Description:Activation of purified human PLK (unknown origin) assessed as ATP production by Kinase-Glo Max luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of purified human PLK (unknown origin) assessed as ATP production by Kinase-Glo Max luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PKL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKL expressed in Escherichia coli preincubated for 15 mins followed by PEP/NADH addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKL expressed in Escherichia coli preincubated for 15 mins followed by PEP/NADH addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of purified human N-terminal His-tagged PK-R by LDH-coupled continuous assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of PKL (unknown origin) for 30 mins by Kinase-Glo Max reagent based luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of purified human N-terminal His-tagged PK-L by LDH-coupled continuous assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKL expressed in Escherichia coli preincubated for 15 mins followed by PEP/NADH addition measur...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity to PKL (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nMAssay Description:Inhibitory constant for inhibition of pyruvate kinase obtained from rat liver (PK-L) was determined using ADP as competitive inhibitorMore data for this Ligand-Target Pair
Affinity DataKi: 8.40E+6nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L) at 3.6 mMMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+6nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L) at 3.6 mMMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+6nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L) at 3.6 mMMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-L)More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+7nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K) at 6.7 mMMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+6nMAssay Description:Inhibition of rat kidney pyruvate kinase (PK-K)More data for this Ligand-Target Pair
