Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with Target = 'Serine racemase'
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648628(CHEMBL5611941)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648628(CHEMBL5611941)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells assessed as dissociation con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50055467(CHEMBL3317781 | CHEBI:17576)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity to serine recemase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648628(CHEMBL5611941)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50038343(CHEMBL3360546)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of mouse serine racemase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648629(CHEMBL5613082)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 2.49E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648631(CHEMBL5614231)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human SR incubated for 30 mins by chemiluminescence based luminometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of mouse serine racemase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to serine recemase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378533(CHEMBL568192)
Affinity DataKi:  4.30E+4nMAssay Description:Inhibition of mouse recombinant serine racemase transfected in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50038343(CHEMBL3360546)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of human recombinant serine racemase expressed in Escherichia coli Rosetta 2 (DE3) cells using L-serine as substrate by horseradish peroxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataKi:  6.60E+4nMAssay Description:Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of mouse recombinant serine racemase transfected in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of human SR extracted from Escherichia coli assessed as beta-eliminase activity using L-Ser as substrate by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378531(CHEMBL566071)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50038354(CHEMBL1794676 | CHEBI:16513)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50055464(CHEMBL3317747)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of serine racemase mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378530(CHEMBL566494)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50185232((S)-2-((S)-3-(1H-imidazol-4-yl)-2-(3-phenylpropana...)
Affinity DataKi:  3.20E+5nMAssay Description:Inhibition of human serine racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataKi:  3.66E+5nMAssay Description:Binding affinity to serine recemase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378532(CHEMBL569435)
Affinity DataIC50: 3.70E+5nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM92990(Aminomalonate)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378532(CHEMBL569435)
Affinity DataKi:  4.17E+5nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by Linewaver-bur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50055465(CHEMBL3317754)
Affinity DataIC50: 5.20E+5nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50185231((2S,3R)-2-((S)-3-(1H-imidazol-4-yl)-2-(3-phenylpro...)
Affinity DataKi:  6.10E+5nMAssay Description:Inhibition of human serine racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50055466(CHEMBL3317759)
Affinity DataIC50: 6.30E+5nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50038342(CHEMBL3360547)
Affinity DataIC50: 7.80E+5nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50453342(CHEMBL4205674)
Affinity DataIC50: 8.36E+5nMAssay Description:Inhibition of wild-type serine racemase (unknown origin) assessed as residual activity by measuring D-serine level using Dsd1 as substrate and PLP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50055464(CHEMBL3317747)
Affinity DataIC50: 1.21E+6nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50129194((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50119563(CHEBI:45969 | TRICARBALLYLIC ACID)
Affinity DataKi:  1.30E+6nMAssay Description:Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 1.31E+6nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50119562(CHEMBL3617724)
Affinity DataKi:  1.50E+6nMAssay Description:Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50119565(CHEMBL3617722)
Affinity DataKi:  1.50E+6nMAssay Description:Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50055464(CHEMBL3317747)
Affinity DataIC50: 1.60E+6nMAssay Description:Inhibition of wild-type serine racemase (unknown origin) assessed as residual activity by measuring D-serine level using Dsd1 as substrate and PLP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50378534(CHEMBL216796)
Affinity DataKi:  1.64E+6nMAssay Description:Inhibition of mouse recombinant serine racemase transfected in bacterial expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50119564(CHEMBL3617723)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50038341(METHYLMALONIC ACID | CHEBI:30860)
Affinity DataIC50: 1.85E+6nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50129194((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...)
Affinity DataKi:  1.90E+6nMAssay Description:Inhibition of mouse brain serine racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50038340(CHEMBL3360548)
Affinity DataIC50: 2.16E+6nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetSerine racemase(Mouse)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50357231(L-CYCLOSERINE)
Affinity DataIC50: 2.27E+6nMAssay Description:Inhibition of mouse SR using L-Serine as substrate incubated for 2 hrs in presence of PLP by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50427212((2S,3R)-2,3-Dihydroxysuccinic Acid | Meso-Tartrate...)
Affinity DataIC50: 2.82E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648630(CHEMBL5614081)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of human SR extracted from Escherichia coli assessed as beta-eliminase activity using L-Ser as substrate by spectrophotometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50119560(CHEMBL3617727)
Affinity DataKi:  4.50E+6nMAssay Description:Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50427205(CHEMBL2324854)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50427209(CHEMBL1497209)
Affinity DataIC50: 5.02E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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