Compile Data Set for Download or QSAR
Report error Found 369 Enz. Inhib. hit(s) with Target = 'Sodium/bile acid cotransporter'
TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50576171(CHEMBL4875567)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells pretreated for 2 hrs followed by [3H]-TCA addition in absence of FBSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSodium/bile acid cotransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150325(3-[4-(4-{[Benzyl-(3-methanesulfonylamino-2-methyl-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]taurocholate uptake in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400082(US10328053, Compound 60 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  1.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400082(US10328053, Compound 60 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  1.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400062(US10328053, Compound 40 | (1aR,6aR)-5-(2-((3,3-dif...)
Affinity DataEC50:  1.90nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400062(US10328053, Compound 40 | (1aR,6aR)-5-(2-((3,3-dif...)
Affinity DataEC50:  1.90nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400063(US10328053, Compound 41 | (1aR,6aR)-N-(3-cyano-4-f...)
Affinity DataEC50:  2.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400064(US10328053, Compound 42 | (1aR,6aR)-5-(2-((3,3-dif...)
Affinity DataEC50:  2.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400064(US10328053, Compound 42 | (1aR,6aR)-5-(2-((3,3-dif...)
Affinity DataEC50:  2.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400061(US10328053, Compound 39 | (1aR,6aR)-N-(3-chloro-4-...)
Affinity DataEC50:  2.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400111(US10328053, Compound 89 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  2.90nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400111(US10328053, Compound 89 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  2.90nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400051(US10328053, Compound 29 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  3.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400051(US10328053, Compound 29 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  3.10nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400075(US10328053, Compound 53 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  3.20nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400053(US10328053, Compound 31 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  3.20nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400053(US10328053, Compound 31 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  3.20nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400075(US10328053, Compound 53 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  3.20nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400121(US10328053, Compound 100 | (1aR,6aR)-5-(2-((3,3-di...)
Affinity DataEC50:  3.70nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400121(US10328053, Compound 100 | (1aR,6aR)-5-(2-((3,3-di...)
Affinity DataEC50:  3.70nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150349(Methanesulfonamide derivative | CHEMBL266407)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]taurocholate uptake in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400033(US10328053, Compound 12 | 7-(2-((1-(1,3,4-thiadiaz...)
Affinity DataEC50:  5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400033(US10328053, Compound 12 | 7-(2-((1-(1,3,4-thiadiaz...)
Affinity DataEC50:  5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400059(US10328053, Compound 37 | N-(3-cyano-4-fluoropheny...)
Affinity DataEC50:  5.60nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400059(US10328053, Compound 37 | N-(3-cyano-4-fluoropheny...)
Affinity DataEC50:  5.60nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400028(US10328053, Compound 7 | N-(3-chloro-4-fluoropheny...)
Affinity DataEC50:  5.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400116(US10328053, Compound 94 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  5.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400116(US10328053, Compound 94 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  5.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400028(US10328053, Compound 7 | N-(3-chloro-4-fluoropheny...)
Affinity DataEC50:  5.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400114(US10328053, Compound 92 | 7-(2-((1-ethynylcyclopro...)
Affinity DataEC50:  6.40nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400114(US10328053, Compound 92 | 7-(2-((1-ethynylcyclopro...)
Affinity DataEC50:  6.40nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400088(US10328053, Compound 66 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  6.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400089(US10328053, Compound 67 | 6-methyl-7-(2-oxo-2-((1-...)
Affinity DataEC50:  6.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400070(US10328053, Compound 48 | (R)-7-(2-((3,3-difluoro-...)
Affinity DataEC50:  6.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400070(US10328053, Compound 48 | (R)-7-(2-((3,3-difluoro-...)
Affinity DataEC50:  6.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400089(US10328053, Compound 67 | 6-methyl-7-(2-oxo-2-((1-...)
Affinity DataEC50:  6.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400088(US10328053, Compound 66 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  6.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400063(US10328053, Compound 41 | (1aR,6aR)-N-(3-cyano-4-f...)
Affinity DataEC50:  7.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400063(US10328053, Compound 41 | (1aR,6aR)-N-(3-cyano-4-f...)
Affinity DataEC50:  7.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400074(US10328053, Compound 52 | (1aR,6aR)-5-(2-((1-(1H-1...)
Affinity DataEC50:  7.70nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400032(US10328053, Compound 11 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  7.70nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400032(US10328053, Compound 11 | N-(3-chloro-4-fluorophen...)
Affinity DataEC50:  7.70nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400074(US10328053, Compound 52 | (1aR,6aR)-5-(2-((1-(1H-1...)
Affinity DataEC50:  7.70nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400076(US10328053, Compound 54 | (1aR,6aR)-5-(2-((1-(1,3,...)
Affinity DataEC50:  7.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400076(US10328053, Compound 54 | (1aR,6aR)-5-(2-((1-(1,3,...)
Affinity DataEC50:  7.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400148(US10328053, Compound 132 | (R)-N-(3-Chloro-4-fluor...)
Affinity DataEC50:  8.30nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400148(US10328053, Compound 132 | (R)-N-(3-Chloro-4-fluor...)
Affinity DataEC50:  8.30nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400054(US10328053, Compound 32 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  8.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400054(US10328053, Compound 32 | 7-(2-((3,3-difluoro-1-(1...)
Affinity DataEC50:  8.5nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM400110(US10328053, Compound 88 | 7-(2-((3-(1H-1,2,3-triaz...)
Affinity DataEC50:  8.70nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
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