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Report error Found 13178 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter'
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB | US20250019357, Com...)
Affinity DataEC50:  13nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620422(US11767305, Compound R-5-MAPB | US20250019357, Com...)
Affinity DataEC50:  29.3nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620423(US11767305, Compound S-6-MAPB | US20250019357, Com...)
Affinity DataEC50:  20.6nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620424(US11767305, Compound R-6-MAPB | US20250019357, Com...)
Affinity DataEC50:  112nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM712788(US20250019357, Compound S-5-MBPB)
Affinity DataEC50:  31.2nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM712789(US20250019357, Compound R-5-MBPB)
Affinity DataEC50:  49.5nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM712792(US20250019357, Compound S-6-MBPB)
Affinity DataEC50:  54.1nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM712796(US20250019357, Compound R-6-MBPB)
Affinity DataEC50:  172nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620429(US11767305, Compound (-)-BK-5-MAPB | US20250019357...)
Affinity DataEC50:  80nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataEC50:  439nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620431(US11767305, Compound (-)-BK-6-MAPB | US20250019357...)
Affinity DataEC50:  72.2nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620432(US11767305, Compound (+)-BK-6-MAPB | US20250019357...)
Affinity DataEC50:  1.28E+3nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM707600(mdma | US20250019357, Compound MDMA)
Affinity DataEC50:  94.3nMAssay Description:Benzofuran derivatives were evaluated for inhibiting the human 5-HT transporter (hSERT) as expressed in CHO cells using an antagonist radioligand ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010589(CHEMBL162375 | 6,7-Dihydro-5H-indeno[5,6-d][1,3]di...)
Affinity DataKd:  0.127nMAssay Description:Binding affinity was determined towards serotonin uptake site in presence of [3H]paroxetine radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010589(CHEMBL162375 | 6,7-Dihydro-5H-indeno[5,6-d][1,3]di...)
Affinity DataKd:  0.104nMAssay Description:Binding affinity was determined towards serotonin uptake site in presence of [3H]paroxetine radioligand in rat brain cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50459929(CHEMBL4228171)
Affinity DataKd:  210nMAssay Description:Binding affinity to human SERT expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474028(CHEMBL41974)
Affinity DataKd:  759nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474030(CHEMBL40396)
Affinity DataKd:  257nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474040(CHEMBL42150)
Affinity DataKd:  1.20E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474025(CHEMBL38468)
Affinity DataKd:  282nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474045(CHEMBL40529)
Affinity DataKd:  661nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474034(CHEMBL440110)
Affinity DataKd:  59nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474046(CHEMBL41027)
Affinity DataKd:  204nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474048(CHEMBL40240)
Affinity DataKd:  525nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474049(CHEMBL40961)
Affinity DataKd:  2.29E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474029(CHEMBL288823)
Affinity DataKd:  468nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474056(CHEMBL41797)
Affinity DataKd:  813nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474059(CHEMBL39282)
Affinity DataKd:  214nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474062(CHEMBL416433)
Affinity DataKd:  229nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474050(CHEMBL289860)
Affinity DataKd:  132nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474064(CHEMBL41237)
Affinity DataKd:  229nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474036(CHEMBL416800)
Affinity DataKd:  813nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474066(CHEMBL41222)
Affinity DataKd:  676nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474058(CHEMBL43524)
Affinity DataKd:  282nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM22199(CHEMBL286991 | GBR-13,069 | CHEMBL112280 | 1-{2-[b...)
Affinity DataKd:  954nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474067(CHEMBL38942)
Affinity DataKd:  331nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474044(CHEMBL39890)
Affinity DataKd:  200nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474041(CHEMBL288914)
Affinity DataKd:  1.82E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474057(CHEMBL41796)
Affinity DataKd:  191nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM22199(CHEMBL286991 | GBR-13,069 | CHEMBL112280 | 1-{2-[b...)
Affinity DataKd:  363nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474047(CHEMBL290536)
Affinity DataKd:  234nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474063(CHEMBL41390)
Affinity DataKd:  741nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474061(CHEMBL41061)
Affinity DataKd:  603nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474042(CHEMBL290365)
Affinity DataKd:  269nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474068(CHEMBL37513)
Affinity DataKd:  2.88E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474033(CHEMBL416245)
Affinity DataKd:  170nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474038(CHEMBL38773)
Affinity DataKd:  1.32E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474069(CHEMBL41606)
Affinity DataKd:  617nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50083200(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[(E)...)
Affinity DataKd:  372nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50474027(CHEMBL40415)
Affinity DataKd:  72nMAssay Description:Inhibition of [125I]RTI-55 binding to human SERT in clonal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 13178 total ) | Next | Last >>
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