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Report error Found 2525 Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 2'
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM82547(SRIF-D-Trp8)
Affinity DataKi:  0.00100nMAssay Description:Displacement of [125I]-somatostatin from human SSTR2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82465(D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Lys-L-Abu-L-Cys(1)-L-...)
Affinity DataKi:  0.00100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82455(BIM-23027 | N-Methylcyclo[L-Ala-L-Tyr-D-Trp-L-Lys-...)
Affinity DataKi:  0.00100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.00160nMAssay Description:Displacement of [125I]-somatostatin from human SSTR2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM84623(NC4-28B)
Affinity DataKi:  0.00200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM84626(BIM 23034)
Affinity DataKi:  0.00200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50537072(CHEMBL440072)
Affinity DataKi:  0.00500nMAssay Description:Displacement of [125I]somatostatin from human SSTR2 expressed in CHO-K1 cell membranes after 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50097783(SRIF-D-Trp8 | D-Trp8 SST-14 | CHEMBL438401 | SOMAT...)
Affinity DataKi:  0.00500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82469(EC5-21 | BIM-23003 | L-Cys(1)-L-Lys-L-Asn-4-Chloro...)
Affinity DataKi:  0.00500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82462(D-Nal-c[Cys-Tyr-D-Trp-Lys-Thr-Cys]-Thr-NH2 | BIM 2...)
Affinity DataKi:  0.00800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing each of the cloned human SRIF receptor (sst-2) subtypesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82469(EC5-21 | BIM-23003 | L-Cys(1)-L-Lys-L-Asn-4-Chloro...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity towards Somatostatin receptor type 2 (hsst2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50103430(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to human somatostatin receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM82462(D-Nal-c[Cys-Tyr-D-Trp-Lys-Thr-Cys]-Thr-NH2 | BIM 2...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Rat)
Tulane University

Curated by PDSP Ki Database
LigandPNGBDBM82255(D-Phe-Cys-Tyr-D-Trp-Lys-Abu-Cys-Nal-NH | NC8-12)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM85357(2-[[(2R,3S)-2-[[4-[(2-Oxo-2,3-dihydro-1H-benzimida...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM84630(BIM 23060)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578123(CHEMBL4872591)
Affinity DataEC50:  0.0130nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578124(CHEMBL4866325)
Affinity DataEC50:  0.0130nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50537063(CHEMBL4590517)
Affinity DataKi:  0.0130nMAssay Description:Displacement of [125I]somatostatin from human SSTR2 expressed in CHO-K1 cell membranes after 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578111(CHEMBL4861425)
Affinity DataEC50:  0.0130nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578122(CHEMBL4849848)
Affinity DataEC50:  0.0140nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50537077(CHEMBL4550617)
Affinity DataKi:  0.0150nMAssay Description:Displacement of [125I]somatostatin from human SSTR2 expressed in CHO-K1 cell membranes after 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50537069(CHEMBL4584764)
Affinity DataKi:  0.0150nMAssay Description:Displacement of [125I]somatostatin from human SSTR2 expressed in CHO-K1 cell membranes after 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578121(CHEMBL4860633)
Affinity DataEC50:  0.0150nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50537066(CHEMBL4541310)
Affinity DataKi:  0.0150nMAssay Description:Displacement of [125I]somatostatin from human SSTR2 expressed in CHO-K1 cell membranes after 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578128(CHEMBL4873269)
Affinity DataEC50:  0.0170nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50537076(CHEMBL4564727)
Affinity DataKi:  0.0180nMAssay Description:Displacement of [125I]somatostatin from human SSTR2 expressed in CHO-K1 cell membranes after 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578126(CHEMBL4853282)
Affinity DataEC50:  0.0190nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50272772(CHEMBL1680 | 10-(4-Amino-butyl)-19-(2-amino-3-phen...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibitory concentration against human somatostatin receptor type 2 in CC531 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50051568(seglitide | CHEMBL311695 | (3S,6S,9S,12R,15S,18S)-...)
Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM144761(US8952128, 20)
Affinity DataKi:  0.0200nM ΔG°:  -61.1kJ/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM144762(US8952128, 21)
Affinity DataKi:  0.0200nM ΔG°:  -61.1kJ/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM144757(US8952128, 15)
Affinity DataKi:  0.0200nM ΔG°:  -61.1kJ/molepH: 7.6 T: 2°CAssay Description:Membranes for in vitro receptor binding assays were obtained by the following procedures. CHO-K1 cells expressing one of the somatostatin receptors w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2015
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50537061(CHEMBL4527856)
Affinity DataKi:  0.0220nMAssay Description:Displacement of [125I]somatostatin from human SSTR2 expressed in CHO-K1 cell membranes after 240 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM82255(D-Phe-Cys-Tyr-D-Trp-Lys-Abu-Cys-Nal-NH | NC8-12)
Affinity DataKi:  0.0240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM82255(D-Phe-Cys-Tyr-D-Trp-Lys-Abu-Cys-Nal-NH | NC8-12)
Affinity DataKi:  0.0240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50341578(3-[4-(3-Aminopropoxy)-7-chloro-3-(3,5-dimethylphen...)
Affinity DataKi:  0.0250nMAssay Description:Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50341575(7-Chloro-3-(3,5-dimethylphenyl)-6-(1-methyl-1H-pyr...)
Affinity DataKi:  0.0250nMAssay Description:Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578120(CHEMBL4858892)
Affinity DataEC50:  0.0270nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM84628(EC5-21)
Affinity DataKi:  0.0280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50272772(CHEMBL1680 | 10-(4-Amino-butyl)-19-(2-amino-3-phen...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50578109(CHEMBL4863880)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at human SSTR2 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins by Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50155307(CHEMBL3781796)
Affinity DataKi:  0.0300nMAssay Description:Displacement of [125I]tyr11-SRIF from human sst2 receptor after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50341572(3-[7-Chloro-3-(3,5-dimethylphenyl)-4-{2-[(2R)-pipe...)
Affinity DataKi:  0.0370nMAssay Description:Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50341574(3-{7-Chloro-3-(3,5-dimethylphenyl)-4-[2-(piperidin...)
Affinity DataKi:  0.0380nMAssay Description:Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM50064772(Ala-Gly-cyclo[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity towards human sst2 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Institute For Research In Biomedicine (Irb Barcelona)

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CB6417646 | CAS_38916-34-6...)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
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