Compile Data Set for Download or QSAR
Report error Found 1768 Enz. Inhib. hit(s) with Target = 'Substance-K receptor'
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007825(CHEMBL291903 | 2-(2-{2-[2-(4-Amino-butyrylamino)-3...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007826(CHEMBL2372949 | 2-(2-{2-[2-(4-Amino-butyrylamino)-...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007827(CHEMBL301841 | 2-(3-{2-[2-(4-Amino-butyrylamino)-3...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001450(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met NH2 | ...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007828(CHEMBL292435 | 2-(1-{2-[2-(4-Amino-butyrylamino)-3...)
Affinity DataEC50: >500nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007829(CHEMBL280020 | 2-(1-{2-[2-(4-Amino-butyrylamino)-3...)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007823(CHEMBL2372953 | 1-{2-[2-(4-Amino-butyrylamino)-3-p...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007831(CHEMBL54622 | 2-(2-{2-[2-(4-Amino-butyrylamino)-3-...)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001450(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met NH2 | ...)
Affinity DataEC50:  167nMAssay Description:Agonist activity was measured at neurokinin-2 receptor in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007830(CHEMBL301477 | 1-{2-[2-(4-Amino-butyrylamino)-3-ph...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007832(CHEMBL299503 | 2-(3-{2-[2-(4-Amino-butyrylamino)-3...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007822(CHEMBL2372954 | 2-(2-{2-[2-(4-Amino-butyrylamino)-...)
Affinity DataEC50: >100nMAssay Description:Agonist activity was measured at neurokinin-2 receptor in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007822(CHEMBL2372954 | 2-(2-{2-[2-(4-Amino-butyrylamino)-...)
Affinity DataEC50: >100nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50007824(CHEMBL293747 | 2-(2-{2-[2-(4-Amino-butyrylamino)-3...)
Affinity DataEC50: >300nMAssay Description:Agonist activity at tachykinin receptor 2 in the rat colon muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  10nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  208nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Phe270Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  48nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  291nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Phe270Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  1.90nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  48nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  2.70nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  3.10nMAssay Description:Compound was evaluated for Kd value against [125I]-NKA on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  26nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd: >1.00E+3nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  3.60nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  2.10nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  4.40nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  34nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  1.30nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  1.96E+3nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50030211((S)-2-{2-[(2R,5S,8R)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50030213((S)-2-{2-[(2R,5S,8R)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50030212((S)-2-{2-[(2R,5S,8R)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50030214((S)-2-{2-[(6R,9S,12R)-6,9-Dibenzyl-12-(3-guanidino...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052519(Hexanedioic acid (1-{1-[1-((3-acetylamino-propyl)-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens(RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052522((S)-2-{2-[(2S,5R,8S)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052516((S)-2-{2-[(3S,6R,9S)-3,6-Dibenzyl-9-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052525((S)-2-{2-[(2S,5R,8S)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052523((R)-1-{(S)-2-[(S)-2-((S)-2-Acetylamino-5-guanidino...)
Affinity DataEC50: >2.00E+5nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052524((S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-m...)
Affinity DataEC50: >2.00E+5nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052517((S)-2-{2-[(6S,9R,12S)-6,9-Dibenzyl-12-(3-guanidino...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052518((S)-2-{2-[(6S,9R,12S)-6,9-Dibenzyl-12-(3-guanidino...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052521((S)-2-{2-[{(S)-2-[(S)-2-((S)-2-Acetylamino-5-guani...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052515((S)-2-{2-[(2S,5R,8S)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50052520((S)-2-{2-[(3S,6R,9S)-3,6-Dibenzyl-9-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration to activate Tachykinin receptor 2 in rat vas deferens (RVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001592(N-{1-[1-(1-{5-[1-(1-Carbamoyl-3-methylsulfanyl-pro...)
Affinity DataEC50:  59nMAssay Description:In vitro agonistic activity against tachykinin receptor 2 of rat colon muscularis mucosae.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001595(CHEMBL407511 | 1-{2-[2-(5-Amino-pentanoylamino)-3-...)
Affinity DataEC50:  1.30E+4nMAssay Description:In vitro agonistic activity against tachykinin receptor 2 of rat colon muscularis mucosae.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001596(3-(2-Acetylamino-6-amino-hexanoylamino)-N-{1-[1-(1...)
Affinity DataEC50:  1.30nMAssay Description:In vitro agonistic activity against tachykinin receptor 2 of rat colon muscularis mucosae.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001597(N-(1-{1-[1-({[1-(1-Carbamoyl-3-methylsulfanyl-prop...)
Affinity DataEC50:  33nMAssay Description:In vitro agonistic activity against tachykinin receptor 2 of rat colon muscularis mucosae.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001594(N-(1-{1-[1-({[1-(1-Carbamoyl-3-methylsulfanyl-prop...)
Affinity DataEC50:  3nMAssay Description:In vitro agonistic activity against tachykinin receptor 2 of rat colon muscularis mucosae.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
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