Compile Data Set for Download or QSAR
Report error Found 738 Enz. Inhib. hit(s) with Target = 'Sucrase-isomaltase'
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291029((2R,3R,4R,5S)-2-Hydroxymethyl-1-((E)-3-trimethylsi...)
Affinity DataKi:  0.150nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50612995(CHEMBL5276586)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50612998(CHEMBL5269400)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50613001(CHEMBL5268739)
Affinity DataKi:  0.210nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50613004(CHEMBL5282029)
Affinity DataKi:  0.240nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50612994(CHEMBL5283777)
Affinity DataKi:  0.310nMAssay Description:Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024139(1-Hydroxymethyl-5-phenethylamino-cyclohexane-1,2,3...)
Affinity DataIC50: 2.30nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291026((2R,3R,4R,5S)-1-[(E)-3-(Dimethyl-phenyl-silanyl)-a...)
Affinity DataKi:  3nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024120(1-Hydroxymethyl-5-[(thiophen-2-ylmethyl)-amino]-cy...)
Affinity DataIC50: 3.30nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50156360(2-Hydroxymethyl-6-nonyl-piperidine-3,4,5-triol | C...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of rat intestinal isomaltase using disaccharideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50373983(CHEMBL268675)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of rat intestinal maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50226273(CHEMBL3349431)
Affinity DataIC50: 4.60nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50373982(CHEMBL402196)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat intestinal maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024119(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Affinity DataIC50: 5.20nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024137(1-Hydroxymethyl-5-(2-hydroxy-2-phenyl-ethylamino)-...)
Affinity DataIC50: 5.80nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024136(5-(3,5-Di-tert-butyl-4-hydroxy-benzylamino)-1-hydr...)
Affinity DataIC50: 6.80nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405395(CHEMBL2051761)
Affinity DataIC50: 7.5nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  8nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  8nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50373981(CHEMBL403239)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of rat intestinal maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024114(5-(Cyclohexylmethyl-amino)-1-hydroxymethyl-cyclohe...)
Affinity DataIC50: 9.30nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405397(CHEMBL2051983)
Affinity DataIC50: 10nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291023((2R,3R,4R,5S)-1-[(E)-3-(tert-Butyl-dimethyl-silany...)
Affinity DataKi:  10nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024118(5-(3,7-Dimethyl-octa-2,6-dienylamino)-1-hydroxymet...)
Affinity DataIC50: 11nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024124(1-Hydroxymethyl-5-(2-hydroxy-1-phenyl-ethylamino)-...)
Affinity DataIC50: 13nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024133(1-Hydroxymethyl-5-(3-phenyl-allylamino)-cyclohexan...)
Affinity DataIC50: 14nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024128(5-(4-Bromo-benzylamino)-1-hydroxymethyl-cyclohexan...)
Affinity DataIC50: 15nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024126(1-Hydroxymethyl-5-[(pyridin-3-ylmethyl)-amino]-cyc...)
Affinity DataIC50: 15nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024117(5-Cyclohexylamino-1-hydroxymethyl-cyclohexane-1,2,...)
Affinity DataIC50: 15nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291034((2R,3R,4R,5S)-2-Hydroxymethyl-1-(5-trimethylsilany...)
Affinity DataKi:  16nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291021((2R,3R,4R,5S)-2-Hydroxymethyl-1-(4-trimethylsilany...)
Affinity DataKi:  16nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291020((2R,3R,4R,5S)-1-[3-(Dimethyl-phenyl-silanyl)-propy...)
Affinity DataKi:  17nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291030((2R,3R,4R,5S)-1-[4-(Dimethyl-phenyl-silanyl)-butyl...)
Affinity DataKi:  18nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataKi:  20nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  24nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50048090(CHEMBL3311519)
Affinity DataIC50: 26nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291020((2R,3R,4R,5S)-1-[3-(Dimethyl-phenyl-silanyl)-propy...)
Affinity DataKi:  27nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 32nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291034((2R,3R,4R,5S)-2-Hydroxymethyl-1-(5-trimethylsilany...)
Affinity DataKi:  33nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405389(CHEMBL2051982)
Affinity DataIC50: 35nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405396(CHEMBL2051762)
Affinity DataIC50: 36nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291030((2R,3R,4R,5S)-1-[4-(Dimethyl-phenyl-silanyl)-butyl...)
Affinity DataKi:  39nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Sucrase in rat intestinal brush border membranes by D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50375510(CHEMBL405957)
Affinity DataIC50: 40nMAssay Description:Inhibition of rat isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Sucrase in rat intestinal brush border membranes by D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50291021((2R,3R,4R,5S)-2-Hydroxymethyl-1-(4-trimethylsilany...)
Affinity DataKi:  40nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

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