Compile Data Set for Download or QSAR
Report error Found 95 Enz. Inhib. hit(s) with Target = 'Threonine--tRNA ligase'
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  5.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50625969(CHEMBL5405159)
Affinity DataKd:  49nMAssay Description:Inhibition of human cytosolic ThrRS assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50625968(CHEMBL5424310)
Affinity DataKd:  126nMAssay Description:Inhibition of human cytosolic ThrRS assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50625967(CHEMBL5430875)
Affinity DataKd:  115nMAssay Description:Inhibition of human cytosolic ThrRS assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  37nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of tRNA Leucin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  166nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of tRNA Threon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  44nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of glycine by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  290nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of L-threonine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  75nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant in presence of ATP by isot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataKd:  35nMAssay Description:Binding affinity to full length recombinant salmonella enterica threonyl-tRNA synthetase assessed as dissociation constant by isothermal titration ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50366646(CHEMBL1163068)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against cognate Staphylococcus aureus threonyl tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604793(CHEMBL5169990)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50129555(CHEMBL70590 | cid_310900 | 2-((1S,8R,9S,11R,13S,15...)
Affinity DataIC50: 43nMAssay Description:Inhibition of Plasmodium falciparum Threonyl tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50426183(CHEMBL2311925)
Affinity DataIC50: 57nMAssay Description:Inhibition of Plasmodium falciparum Threonyl tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625969(CHEMBL5405159)
Affinity DataIC50: 100nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604786(CHEMBL5204569)
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50366646(CHEMBL1163068)
Affinity DataIC50: 160nMAssay Description:Inhibition of Plasmodium falciparum Threonyl tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50426177(CHEMBL2316961)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604788(CHEMBL5176566)
Affinity DataIC50: 194nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625960(CHEMBL5438745)
Affinity DataIC50: 440nMAssay Description:Inhibition of Plasmodium falciparum Threonyl tRNA synthetaseMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604784(CHEMBL5202947)
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604790(CHEMBL5203381)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604791(CHEMBL5199866)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604794(CHEMBL5205862)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625968(CHEMBL5424310)
Affinity DataIC50: 700nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625967(CHEMBL5430875)
Affinity DataIC50: 800nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604789(CHEMBL5205776)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604787(CHEMBL5183365)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604792(CHEMBL5190774)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604783(CHEMBL5196812)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604781(CHEMBL5181733)
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604795(CHEMBL5183449)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604782(CHEMBL5202536)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604780(CHEMBL5169920)
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604779(CHEMBL5180291)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Salmonella enterica)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50604785(CHEMBL5181263)
Affinity DataIC50: 6.63E+3nMAssay Description:Inhibition of recombinant salmonella enterica threonyl-tRNA synthetase assessed as reduction in enzyme activity incubated for 20 min by Kinase Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThreonine--tRNA ligase(Soybean stem and root rot agent)
Northeast Agricultural University

Curated by ChEMBL
LigandPNGBDBM50129555(CHEMBL70590 | cid_310900 | 2-((1S,8R,9S,11R,13S,15...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of C-terminal His6-tagged Phytophthora sojae race 1 recombinant ThrRS expressed in Escherichia coli BL21 (Codonplus DE3) assessed as reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625964(CHEMBL5431275)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625961(CHEMBL5400120)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Plasmodium falciparum Threonyl tRNA synthetaseMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625963(CHEMBL5409797)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625962(CHEMBL5400764)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625965(CHEMBL5421305)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Targetthreonine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50625966(CHEMBL5413883)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of 6xHis-tag recombinant Plasmodium falciparum threonyl tRNA synthetase expressed in Escherichia using L-threonine and total tRNA by lumin...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase(Yersinia pestis)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426188(CHEMBL2311920)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50426188(CHEMBL2311920)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase(Yersinia pestis)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426182(CHEMBL2311926)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase(Yersinia pestis)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426183(CHEMBL2311925)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50426182(CHEMBL2311926)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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