Compile Data Set for Download or QSAR
Report error Found 315 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 1'
TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577380(US11472815, Compound 1)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577381(US11472815, Compound 2)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577382(US11472815, Compound 3)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577383(US11472815, Compound 4)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577384(US11472815, Compound 5)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577385(US11472815, Compound 9)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577386(US11472815, Compound 11)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577387(US11472815, Compound 15)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577388(US11472815, Compound 18)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577389(US11472815, Compound 21)
Affinity DataEC50:  24.9nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM50552134(CHEMBL4759149 | US11472815, Compound 22)
Affinity DataEC50:  4.88nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577391(US11472815, Compound 23)
Affinity DataEC50:  5.14nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577392(US11472815, Compound 24)
Affinity DataEC50:  433nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577393(US11472815, Compound 25)
Affinity DataEC50:  45.6nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577394(US11472815, Compound 26)
Affinity DataEC50:  192nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577395(US11472815, Compound 27)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577396(US11472815, Compound 28)
Affinity DataEC50:  92.3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577397(US11472815, Compound 29)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577398(US11472815, Compound 30)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577399(US11472815, Compound 31)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577400(US11472815, Compound 32)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577401(US11472815, Compound 33)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577402(US11472815, Compound 34)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577403(US11472815, Compound 35)
Affinity DataEC50:  18.8nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577404(US11472815, Compound 36)
Affinity DataEC50:  56.3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577405(US11472815, Compound 37)
Affinity DataEC50:  113nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577406(US11472815, Compound 38)
Affinity DataEC50:  16.9nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577407(US11472815, Compound 39)
Affinity DataEC50:  12nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577408(US11472815, Compound 40)
Affinity DataEC50:  49.1nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577409(US11472815, Compound 41)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577410(US11472815, Compound 42)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577411(US11472815, Compound 43)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577412(US11472815, Compound 44)
Affinity DataEC50:  764nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577413(US11472815, Compound 45)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577414(US11472815, Compound 46 | US11472815, Compound 47)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1/2(Human)
Southern Medical University

US Patent
LigandPNGBDBM577414(US11472815, Compound 46 | US11472815, Compound 47)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR1/2 in human THP-1 cells assessed as increase in TNF-alpha release incubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600847(CHEMBL5179242)
Affinity DataEC50:  200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600848(CHEMBL5190772)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600849(CHEMBL5176430)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600850(CHEMBL5206865)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600851(CHEMBL5183767)
Affinity DataEC50:  45nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600852(CHEMBL5199615)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600853(CHEMBL5172955)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600854(CHEMBL5201018)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600855(CHEMBL5182057)
Affinity DataEC50:  90nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600856(CHEMBL5201843)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600857(CHEMBL5177664)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetToll-like receptor 1(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50600858(CHEMBL5206661)
Affinity DataEC50:  1nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
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