Compile Data Set for Download or QSAR
Report error Found 595 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 2'
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50358550(CHEMBL1923549 | US9676818, 6d)
Affinity DataEC50:  3.63E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50386539(CHEMBL2048067 | US9676818, 6e)
Affinity DataEC50:  4.79E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50386534(CHEMBL2048075 | US9676818, 11d)
Affinity DataEC50:  1.01E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50386538(CHEMBL2048076 | US9676818, 11e)
Affinity DataEC50:  1.64E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50386537(CHEMBL2048077 | US9676818, 11f)
Affinity DataEC50:  3.80E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50386535(CHEMBL2048219 | US9676818, 11h)
Affinity DataEC50:  4.45E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199102(US9676818, chem-us-00156)
Affinity DataEC50:  2.97E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199104(US9676818, 14b)
Affinity DataEC50:  5.47E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199106(US9676818, 14c)
Affinity DataEC50:  5.95E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50386536(CHEMBL2048220 | US9676818, 16)
Affinity DataEC50:  5.52E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199112(US9676818, 23)
Affinity DataEC50:  225nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199114(US9676818, 25)
Affinity DataEC50:  6.81E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199116(US9676818, 26)
Affinity DataEC50:  7.10E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199302(US9676818, 27)
Affinity DataEC50:  518nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199309(US9676818, 28)
Affinity DataEC50:  1.27E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199327(US9676818, 34)
Affinity DataEC50:  1.18E+4nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199328(US9676818, 38)
Affinity DataEC50:  6.41E+5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199329(US9676818, 41)
Affinity DataEC50:  2.60E+5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199330(US9676818, 45)
Affinity DataEC50:  323nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199331(US9676818, 48)
Affinity DataEC50:  61.5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199332(US9676818, 52)
Affinity DataEC50:  279nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199433(US9676818, 54)
Affinity DataEC50:  2.21E+5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199434(US9676818, 65)
Affinity DataEC50:  1.13E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199435(US9676818, 66)
Affinity DataEC50:  808nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199436(US9676818, 82)
Affinity DataEC50:  182nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199461(US9676818, 83)
Affinity DataEC50:  345nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199462(US9676818, 84)
Affinity DataEC50:  1.50E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199463(US9676818, 85)
Affinity DataEC50:  3.08E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199473(US9676818, 86)
Affinity DataEC50:  1.29E+4nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199474(US9676818, 87)
Affinity DataEC50:  2.07E+4nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199475(US9676818, 88)
Affinity DataEC50:  9.52E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM199481(US9676818, 89)
Affinity DataEC50:  4.78E+3nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50239681(CHEMBL4074408)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kB activation-mediated SEAP production after 24 hrs by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2019
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503931(CHEMBL4522351)
Affinity DataEC50:  4.52E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK cells assessed as induction of MCP1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503932(CHEMBL4443960)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503933(CHEMBL4436542)
Affinity DataEC50:  3.09E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK cells assessed as induction of MCP1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503934(CHEMBL4469379)
Affinity DataEC50:  7.56E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK cells assessed as induction of MCP1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503932(CHEMBL4443960)
Affinity DataEC50:  1.35E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK cells assessed as induction of MCP1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503934(CHEMBL4469379)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503935(CHEMBL4465403)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503931(CHEMBL4522351)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503936(CHEMBL4514785)
Affinity DataEC50:  1.86E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK cells assessed as induction of MCP1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503933(CHEMBL4436542)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503937(CHEMBL4464681)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503938(CHEMBL4556264)
Affinity DataEC50:  1.45E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50503936(CHEMBL4514785)
Affinity DataEC50:  1.35E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50511982(CHEMBL4460494)
Affinity DataEC50:  350nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as activation of SEAP incubated for 24 hrs by quanti-blue SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50511983(CHEMBL4446272)
Affinity DataEC50:  4.52E+4nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as activation of SEAP incubated for 24 hrs by quanti-blue SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50511984(CHEMBL4581678)
Affinity DataEC50:  560nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as activation of SEAP incubated for 24 hrs by quanti-blue SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

US Patent
LigandPNGBDBM50511985(CHEMBL4447292)
Affinity DataEC50:  8.55E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as activation of SEAP incubated for 24 hrs by quanti-blue SEAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
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