Compile Data Set for Download or QSAR
Report error Found 3011 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 1'
TargetUbiquitin carboxyl-terminal hydrolase 13(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50412353(CHEMBL5266862)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to biotinylated USP13 zinc finger ubiquitin binding domain (183 to 307 residues) (unknown origin) expressed in Escherichia coli incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 16(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50412353(CHEMBL5266862)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to biotinylated USP16 zinc finger ubiquitin binding domain (25 to 185 residues) (unknown origin) expressed in Escherichia coli incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50608543(CHEMBL4441423)
Affinity DataKd:  1.40E+4nMAssay Description:Inhibition of human his tagged USP14 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 16(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50627659(CHEMBL5410606)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to N-terminal Avi-tagged and C-terminal His6-tagged USP16 (25 to 185 residues) (unknown origin) expressed in Escherichia coli BirA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 16(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50627660(CHEMBL5426708)
Affinity DataKd:  4.90E+3nMAssay Description:Binding affinity to N-terminal Avi-tagged and C-terminal His6-tagged USP16 (25 to 185 residues) (unknown origin) expressed in Escherichia coli BirA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50635245(CHEMBL5549757)
Affinity DataKd:  5.24E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  39nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  4.33E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  3.65E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM324798(9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324799(9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324809(9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324810(9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324811(9-(4-(1H-pyrazol-1- | US10189841, Compound I-17 | ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324822(9-(4-(1H-pyrazol-1- | US10189841, Compound I-28 | ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324906(9-(((1r,4r)-4-(3,5- | US10189841, Compound I-112 |...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324938(2-(2-isopropylphenyl)-9-(1- | US10189841, Compound...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324947(2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324948(9-(4-(1H-1,2,4-triazol-1- | US10189841, Compound I...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324950((S)-2-(2-isopropylphenyl)- | US10189841, Compound ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324976(2-(2-isopropylphenyl)-9- | US10189841, Compound I-...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM324977(2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325028(9-(4-(3-(dimethylamino)propoxy)benzyl)-2-(2- | US1...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325033(9-(3-(cyclopropylmethoxy)benzyl)-2-(2- | US1018984...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325036(2-(2-isopropylphenyl)-7-methyl-9-(3-(pyridin-2- | ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325038(9-(3-(2-(dimethylamino)ethoxy)benzyl)-2-(2- | US10...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325039(9-(3-(3-(dimethylamino)propoxy)benzyl)-2-(2- | US1...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325040(9-(3-cyclobutoxybenzyl)-2-(2-isopropylphenyl)-7- |...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325048(2-(4-(4-((2-(2-isopropylphenyl)-8-oxo-7,8-dihydro-...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325079(US10189841, Compound I-298 | 2-(2-isopropylphenyl)...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325132(9-(4-(4-(2-aminopropan-2-yl)-1H-1,2,3-triazol-1- |...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325133(9-(4-(4-((dimethylamino)methyl)-1H-1,2,3-triazol-1...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325140(9-(4-(4-((diethylamino)methyl)-1H-1,2,3-triazol-1-...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325141((R)-9-(4-(4-(1-hydroxyethyl)-1H-1,2,3-triazol-1- |...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325142(9-(4-(4-(3-aminopentan-3-yl)-1H-1,2,3-triazol-1- |...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325144(2-(2-isopropylphenyl)-9-(4-(4-((methylsulfonyl)met...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325171(9-(4-(3-hydroxyazetidine-1-carbonyl)benzyl)-2-(2- ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325202(N-(2-(dimethylamino)ethyl)-4-((2-(2- | US10189841,...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325203(4-((2-(2-isopropylphenyl)-8-oxo-7,8-dihydro-9H- | ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325204(2-(2-isopropylphenyl)-9-(4-(4-methylpiperazine-1- ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325229(2-(2-isopropylpyridin- | US10189841, Compound I-43...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325236(2-(2-isopropylpyridin-3- | US10189841, Compound I-...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325243(2-(2-isopropylphenyl)-7- | US10189841, Compound I-...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325247(N-(4-((2-(2-isopropylphenyl)- | US10189841, Compou...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325249(N-(4-((2-(2-isopropylphenyl)- | US10189841, Compou...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325256(9-((1- | US10189841, Compound I-462 | US10399980, ...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325264(N-(4-((2-(2- | US10189841, Compound I-470 | US1039...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325265(N-(4-((2-(2- | US10189841, Compound I-471 | US1039...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325269(9-((4-fluoro-1- | US10189841, Compound I-475 | US1...)
Affinity DataIC50: 0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

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