UniProt Accession IDs for Pathway Inhibition of Signaling by Overexpressed EGFR

The UniProt or TrEMBL identifiers listed in this pages are extracted from UniProt2Reactome_All_Levels.txt, whose links of the affinity data in BindingDB are also listed.

  1. Primary ID
    UniProt Recommended Name
    Secondary IDs
    BindingDB Name
    Affinity Link(s)
    Articles
    Downloads
  2. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-751,75360-1210]
    IC50: 2
    1
    2D 3D TSV
  3. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-746,753-1210,P753S]
    IC50: 2
    1
    2D 3D TSV
  4. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-746,750-1210,A750P]
    IC50: 2
    1
    2D 3D TSV
  5. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [668-1210,T790M,L858R]
    IC50: 26 EC50: 2
    3
    2D 3D TSV
  6. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [645-1186]
    IC50: 33
    1
    2D 3D TSV
  7. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [T790M]
    IC50: 229
    12
    2D 3D TSV
  8. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-745,751-967]
    EC50: 8
    1
    2D 3D TSV
  9. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor (EGFR)(L858R)(T790M)
    IC50: 1206 Kd: 13 EC50: 18
    38
    2D 3D TSV
  10. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [L858R]
    IC50: 317 Kd: 22
    15
    2D 3D TSV
  11. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-973]
    IC50: 17
    4
    2D 3D TSV
  12. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-999,L858R]
    IC50: 2 Kd: 16
    2
    2D 3D TSV
  13. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [G719C]
    IC50: 2 Kd: 21
    3
    2D 3D TSV
  14. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [696-1210,T790M]
    IC50: 5
    2
    2D 3D TSV
  15. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [668-1210]
    IC50: 11 EC50: 2
    3
    2D 3D TSV
  16. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [671-1210,L858R]
    IC50: 10
    1
    2D 3D TSV
  17. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [696-1022,T790M,L858R]
    Kd: 2
    1
    2D 3D TSV
  18. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [696-1022,T790M]
    Kd: 2
    1
    2D 3D TSV
  19. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [696-1022,L858R]
    IC50: 7 Kd: 4
    3
    2D 3D TSV
  20. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [696-1022,G719S]
    Kd: 2
    1
    2D 3D TSV
  21. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-763,'FHEA',764-1210]
    IC50: 106
    2
    2D 3D TSV
  22. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-745,751-1210,T790M,C797S]
    IC50: 8
    1
    2D 3D TSV
  23. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-745,751-1210,C797S]
    IC50: 8
    1
    2D 3D TSV
  24. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-769,'ASV',770-1210]
    IC50: 102
    1
    2D 3D TSV
  25. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-773,'NPH',774-1210]
    IC50: 103
    1
    2D 3D TSV
  26. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-772,'NPH',773-1210]
    IC50: 12
    1
    2D 3D TSV
  27. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-769,'SV',770-1210]
    IC50: 58
    1
    2D 3D TSV
  28. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-769,'SVD',770-1210]
    IC50: 58
    1
    2D 3D TSV
  29. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-770,'NPG',771-1210]
    IC50: 69 Kd: 1
    3
    2D 3D TSV
  30. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-770,'SVD',771-1210]
    IC50: 146
    2
    2D 3D TSV
  31. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [S768I]
    IC50: 58
    1
    2D 3D TSV
  32. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [669-770,'SVD',771-1210]
    IC50: 73
    2
    2D 3D TSV
  33. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [L858R,C797S]
    IC50: 200
    5
    2D 3D TSV
  34. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-18,20-1210,T790M]
    IC50: 95
    4
    2D 3D TSV
  35. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-18,20-1210]
    IC50: 150
    4
    2D 3D TSV
  36. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-18,20-1210,T790M,C797S]
    IC50: 465
    8
    2D 3D TSV
  37. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-18,20-745,751-1210,T790M,C797S]
    IC50: 428
    5
    2D 3D TSV
  38. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [695-1022]
    IC50: 142
    1
    2D 3D TSV
  39. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [695-1022,T790M,C797S,L858R]
    IC50: 143
    1
    2D 3D TSV
  40. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [695-745,751-1022,T790M,C797S]
    IC50: 49
    1
    2D 3D TSV
  41. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [L858R,T790M,C797S]
    IC50: 465
    8
    2D 3D TSV
  42. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-18,20-745,747-749,751-1210,T790M]
    IC50: 29
    1
    2D 3D TSV
  43. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-18,20-745,747-749,751-1210]
    IC50: 29
    1
    2D 3D TSV
  44. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-745,751-1210,T790M]
    IC50: 10
    2
    2D 3D TSV
  45. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-746,748-750,752-1210]
    Kd: 1
    1
    2D 3D TSV
  46. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-746,748-751,753-1210,P753S]
    Kd: 1
    1
    2D 3D TSV
  47. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-746,748-748,750-1210,A750P]
    Kd: 1
    1
    2D 3D TSV
  48. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [L861Q]
    IC50: 2 Kd: 1
    2
    2D 3D TSV
  49. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [G719S]
    IC50: 2 Kd: 1
    2
    2D 3D TSV
  50. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-751,753-758,760-1210]
    Kd: 8
    1
    2D 3D TSV
  51. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-745,747-749,751-1210]
    IC50: 4 Kd: 8
    1
    2D 3D TSV
  52. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-249,301-1210,T790M,L858R]
    IC50: 23
    1
    2D 3D TSV
  53. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-745,751-1210]
    IC50: 53 Kd: 3
    4
    2D 3D TSV
  54. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor
    Ki: 305 IC50: 19048 Kd: 1554 EC50: 274
    1134
    2D 3D TSV
  55. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-770,'NPG',771-1210,T790M]
    IC50: 8
    1
  56. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [1-18,20-745,751-1210,T790M]
    IC50: 80
    1
    2D 3D TSV
  57. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [669-1210]
    IC50: 165
    1
    2D 3D TSV
  58. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor [T790M,C797S,L858R]
    IC50: 275
    3
    2D 3D TSV
  59. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2
    IC50: 40
    3
    2D 3D TSV
  60. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal/Hepatocyte growth factor receptor
    IC50: 3
    1
    2D 3D TSV
  61. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor
    Ki: 170 IC50: 495 Kd: 2 EC50: 49
    31
    2D 3D TSV
  62. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    Epidermal growth factor receptor/Interleukin-3
    IC50: 12
    1
    2D 3D TSV
  63. P00533
    Epidermal growth factor receptor
    O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
    ...
    Ki: 475 IC50: 25087 Kd: 1663 EC50: 353
    1171
    2D 3D TSV
  64. Q99075
    Proheparin-binding EGF-like growth factor
    B2R821
    Proheparin-binding EGF-like growth factor
    Kd: 3
    1
    2D 3D TSV