UniProt Accession IDs for Pathway SHOC2 M1731 mutant abolishes MRAS complex function

The UniProt or TrEMBL identifiers listed in this pages are extracted from UniProt2Reactome_All_Levels.txt, whose links of the affinity data in BindingDB are also listed.

  1. Primary ID
    UniProt Recommended Name
    Secondary IDs
    BindingDB Name
    Affinity Link(s)
    Articles
    Downloads
  2. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase
    Ki: 23 IC50: 4682 Kd: 526 EC50: 23
    187
    2D 3D TSV
  3. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [305-648]
    IC50: 1
    1
    2D 3D TSV
  4. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [325-648]
    IC50: 22
    1
    2D 3D TSV
  5. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D]
    IC50: 127
    6
    2D 3D TSV
  6. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D]
    IC50: 96
    2
    2D 3D TSV
  7. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E]
    IC50: 1923
    3
    2D 3D TSV
  8. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [1-324]
    IC50: 65
    3
    2D 3D TSV
  9. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase/Serine/threonine-protein kinase B-raf
    EC50: 2
    1
    2D 3D TSV
  10. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    Dual specificity mitogen-activated protein kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase
    IC50: 26
    2
    2D 3D TSV
  11. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    GTPase KRas [1-169,G12V,C118S]/RAF proto-oncogene serine/threonine-protein kinase
    IC50: 48
    1
    2D 3D TSV
  12. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V]
    IC50: 181
    1
    2D 3D TSV
  13. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    GTPase KRas [G12V]/RAF proto-oncogene serine/threonine-protein kinase
    IC50: 147
    1
    2D 3D TSV
  14. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    GTPase KRas [1-169]/RAF proto-oncogene serine/threonine-protein kinase
    IC50: 96
    1
    2D 3D TSV
  15. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    GTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase
    IC50: 45
    2
    2D 3D TSV
  16. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF Proto-oncogen Serine/Threonine-Protein Kinase/GTPase KRas [1-169,G12C,C51S,C80L,C118S]
    IC50: 320
    1
  17. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [50-132]/GTPase KRas [1-169,G12D]
    IC50: 16
    1
    2D 3D TSV
  18. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    Mitogen-activated protein kinase kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase
    Kd: 38
    1
    2D 3D TSV
  19. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    GTPase KRas/RAF proto-oncogene serine/threonine-protein kinase
    IC50: 18
    1
    2D 3D TSV
  20. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    RAF proto-oncogene serine/threonine-protein kinase [50-132]/GTPase KRas [G12D]
    IC50: 62
    1
    2D 3D TSV
  21. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    KRAS (G12D)/Son of Sevenless Homolog 1 (SOS)/RAF Proto-Oncogene Serine/Threonine-Protein Kinase (c-Raf)
    IC50: 21
    1
    2D 3D TSV
  22. P04049
    RAF proto-oncogene serine/threonine-protein kinase
    B0LPH8 B2R5N3 Q15278 Q9UC20
    ...
    Ki: 23 IC50: 7918 Kd: 564 EC50: 25
    211
    2D 3D TSV