Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 10528
TargetTyrosine-protein kinase JAK2(Human)
Turning Point Therapeutics

US Patent
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 1.04nMAssay Description:The kinase inhibition IC50 was determined at Reaction Biology Corporation (www.reactionbiology.com, Malvern, Pa.) following the procedures described ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Turning Point Therapeutics

US Patent
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 5.29nMAssay Description:The kinase inhibition IC50 was determined at Reaction Biology Corporation (www.reactionbiology.com, Malvern, Pa.) following the procedures described ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Turning Point Therapeutics

US Patent
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 6.96nMAssay Description:The kinase inhibition IC50 was determined at Reaction Biology Corporation (www.reactionbiology.com, Malvern, Pa.) following the procedures described ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent