Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50008687
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 0.505nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076073(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 6.20nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076070(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 8nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 21nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 26nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 51nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 89nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 103nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076070(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 135nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 188nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 194nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076066(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 203nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 250nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 256nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 257nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 472nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, thrombin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076066(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 479nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076073(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 791nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 1.22E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 1.22E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.36E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076070(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076073(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076066(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076070(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076071(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076073(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076072(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076069(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Factor Xa cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076066(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076068(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076067(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Concentration required for the in vitro inhibitory activity against human enzyme, Plasmin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed