Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50036805
TargetDelta-type opioid receptor(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.0620nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor delta 1 of guinea pig caudate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076495(16-methoxy-22-methyl-(13R)-14-oxa-11,22-diazahepta...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  3.20nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor mu 1 of guinea pig caudate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  7nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  8.90nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor kappa 1 of guinea pig caudate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  22nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor delta 1 of guinea pig caudateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076499(24-cyclopropylmethyl-19-methoxy-4,24-diazahexacycl...)
Affinity DataKi:  22nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  27nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  30nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076495(16-methoxy-22-methyl-(13R)-14-oxa-11,22-diazahepta...)
Affinity DataKi:  30nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076495(16-methoxy-22-methyl-(13R)-14-oxa-11,22-diazahepta...)
Affinity DataKi:  66nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076498(6,7-Didehydro-4-hydroxy-3-methoxy-17-methyl-6,7:2'...)
Affinity DataKi:  94nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi:  218nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076497(6,7-Dedihydro-17-ethyl-4-hydroxy-3-methoxymethyl-6...)
Affinity DataKi:  515nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076500(24-ethyl-19-methoxy-4,24-diazahexacyclo[12.7.3.01,...)
Affinity DataKi:  684nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076500(24-ethyl-19-methoxy-4,24-diazahexacyclo[12.7.3.01,...)
Affinity DataKi:  797nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi: >1.25E+3nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor kappa 1 of guinea pig caudateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi: >1.25E+3nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor mu 1 of guinea pig caudate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076497(6,7-Dedihydro-17-ethyl-4-hydroxy-3-methoxymethyl-6...)
Affinity DataKi:  1.35E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076499(24-cyclopropylmethyl-19-methoxy-4,24-diazahexacycl...)
Affinity DataKi:  1.85E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076498(6,7-Didehydro-4-hydroxy-3-methoxy-17-methyl-6,7:2'...)
Affinity DataKi:  2.82E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi:  2.85E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076499(24-cyclopropylmethyl-19-methoxy-4,24-diazahexacycl...)
Affinity DataKi:  3.16E+3nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076497(6,7-Dedihydro-17-ethyl-4-hydroxy-3-methoxymethyl-6...)
Affinity DataKi:  3.64E+3nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076500(24-ethyl-19-methoxy-4,24-diazahexacyclo[12.7.3.01,...)
Affinity DataKi: >5.30E+3nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi: >6.70E+3nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076498(6,7-Didehydro-4-hydroxy-3-methoxy-17-methyl-6,7:2'...)
Affinity DataKi: >6.80E+3nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  7.92E+3nMAssay Description:Binding affinity towards Opioid receptor kappa 1 by the displacement of [3H]U-69593 radioligand in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  1.33E+4nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed