Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50008885
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078235(2-(2,4-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-met...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078228(2-(2,6-Dichloro-phenyl)-7-ethyl-5-(2-methoxy-pheny...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078226(2-(2,6-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-met...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078229(2-(2,6-Dichloro-phenyl)-5-(3-methoxy-phenyl)-7-met...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078231(2-(2,6-Dichloro-phenyl)-5-(2-isopropoxy-phenyl)-7-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078237(5-(2-Chloro-phenyl)-2-(2,6-dichloro-phenyl)-7-meth...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078236(2-(2,6-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-met...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078230(2-(2,6-Dichloro-phenyl)-5-(2-ethoxy-phenyl)-7-meth...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078239(2-(2,6-Dichloro-phenyl)-5-(2-fluoro-phenyl)-7-meth...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078232(2-(2,6-Dichloro-phenyl)-7-isopropyl-5-(2-methoxy-p...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078238(2-(2,6-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-met...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078234(2-(4-Chloro-phenyl)-5-(2-methoxy-phenyl)-7-methyl-...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078227(2-(2,6-Dichloro-phenyl)-5-(4-methoxy-phenyl)-7-met...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078225(2-(2,6-Dichloro-phenyl)-7-methyl-5-o-tolyl-5H-thia...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078233(2-(2,6-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-met...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50078224(7-Benzoyl-2-(2,6-dichloro-phenyl)-5-(2-methoxy-phe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 1S,3R-ACPD (10 uM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed