Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50008891
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50043604(17-tert-Butylcarbamoyl-10,13-dimethyl-2,7,8,9,10,1...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human Steroid 5-alpha-reductase type 2 using 18213 3H testosterone 210 nM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50043604(17-tert-Butylcarbamoyl-10,13-dimethyl-2,7,8,9,10,1...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against rat Steroid 5-alpha-reductase type I using 18213 3H testosterone 210 nM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50043604(17-tert-Butylcarbamoyl-10,13-dimethyl-2,7,8,9,10,1...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against human Steroid 5-alpha-reductase type I in DU 145 cell culture using 3H androstenedione 5 nM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50078264(4-(1-Cyclohexylmethyl-1H-indol-5-yl)-benzoic acid ...)
Affinity DataIC50: 2.10E+6nMAssay Description:Inhibitory concentration against human Steroid 5-alpha-reductase type I in DU 145 cell culture using 3H androstenedione 5 nM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50078265(4-(1-Benzhydryl-1H-indol-5-yl)-benzoic acid | CHEM...)
Affinity DataIC50: 2.78E+6nMAssay Description:Inhibitory concentration against human Steroid 5-alpha-reductase type I in DU 145 cell culture using 3H androstenedione 5 nM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50078266(4-[1-(1-Propyl-butyl)-1H-indol-5-yl]-benzoic acid ...)
Affinity DataIC50: 3.20E+6nMAssay Description:Inhibitory concentration against human Steroid 5-alpha-reductase type I in DU 145 cell culture using 3H androstenedione 5 nM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50078267(4-(1-Benzyl-1H-indol-5-yl)-benzoic acid | CHEMBL40...)
Affinity DataIC50: 6.20E+6nMAssay Description:Inhibitory activity against human 5-alpha-reductase type 2 using 18213 3H testosterone 210 nM as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed