Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50008927
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078592((R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromet...)
Affinity DataIC50: 140nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078591(3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-2-(...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078588(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078592((R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromet...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078590(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078587(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078589((1S,2R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluor...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078595((S)-3-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromet...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50215533(CHEMBL296220)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078594((S)-3-Ethyl-2-[3-(4-methanesulfonyl-phenyl)-5-trif...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078585(3-(4-Methanesulfonyl-phenyl)-2-(2,2,2-trifluoro-et...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078586(2-(4-Chloro-benzyloxy)-3-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078593([3'-(4-Methanesulfonyl-phenyl)-5'-trifluoromethyl-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in CHO whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50215533(CHEMBL296220)
Affinity DataIC50: 400nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078595((S)-3-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromet...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078591(3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-2-(...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078585(3-(4-Methanesulfonyl-phenyl)-2-(2,2,2-trifluoro-et...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078588(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078593([3'-(4-Methanesulfonyl-phenyl)-5'-trifluoromethyl-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078590(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50215533(CHEMBL296220)
Affinity DataIC50: 1.24E+3nMAssay Description:In vitro inhibitory concentration required against Cyclooxygenase-1 (COX-1) determined in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078589((1S,2R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluor...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078587(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078594((S)-3-Ethyl-2-[3-(4-methanesulfonyl-phenyl)-5-trif...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078592((R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromet...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078586(2-(4-Chloro-benzyloxy)-3-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078588(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078593([3'-(4-Methanesulfonyl-phenyl)-5'-trifluoromethyl-...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078587(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078585(3-(4-Methanesulfonyl-phenyl)-2-(2,2,2-trifluoro-et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078586(2-(4-Chloro-benzyloxy)-3-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078589((1S,2R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluor...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078594((S)-3-Ethyl-2-[3-(4-methanesulfonyl-phenyl)-5-trif...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078590(1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078591(3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-2-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50078595((S)-3-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromet...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human whole blood (HWB) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed