Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50009051
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 6nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 15nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 35nMAssay Description:Compound was tested for inhibitory activity against ACAT from U937 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 36nMAssay Description:Compound was tested for inhibitory activity against ACAT from HepG2 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 36nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 43nMAssay Description:Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 45nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 56nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 89nMAssay Description:Compound was tested for inhibitory activity against ACAT from HepG2 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 113nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 130nMAssay Description:Compound was tested for inhibitory activity against ACAT from U937 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 137nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 141nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 152nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 191nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 228nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 281nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079715(Tetradecanethioic acid (2,6-diisopropyl-phenyl)-am...)
Affinity DataIC50: 554nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 619nMAssay Description:Compound was tested for inhibitory activity against ACAT from U937 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 838nMAssay Description:Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 926nMAssay Description:Compound was tested for inhibitory activity against ACAT from HepG2 microsome in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 1.95E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from rabbit adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 3.57E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 4.59E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 4.65E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 5.87E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Human)
Azwell

Curated by ChEMBL
LigandPNGBDBM50079716((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...)
Affinity DataIC50: 7.24E+3nMAssay Description:Compound was tested for inhibitory activity against ACAT from canine intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed