Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50035012
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080157((RS)-tacrine(10)-hupyridone | 5-[10-(1,2,3,4-Tetra...)
Affinity DataIC50: 8.80nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080160(5-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyla...)
Affinity DataIC50: 26nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080162(5-[9-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-nonyla...)
Affinity DataIC50: 36nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366608(CHEMBL1202834)
Affinity DataIC50: 37nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366606(CHEMBL1202835)
Affinity DataIC50: 43nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366605(CHEMBL1202836)
Affinity DataIC50: 53nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080157((RS)-tacrine(10)-hupyridone | 5-[10-(1,2,3,4-Tetra...)
Affinity DataIC50: 82nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 92nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080164(5-[12-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-dodec...)
Affinity DataIC50: 112nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataIC50: 114nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366607(CHEMBL1202837)
Affinity DataIC50: 122nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 149nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080162(5-[9-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-nonyla...)
Affinity DataIC50: 150nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080160(5-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyla...)
Affinity DataIC50: 166nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366607(CHEMBL1202837)
Affinity DataIC50: 220nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 223nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366608(CHEMBL1202834)
Affinity DataIC50: 223nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366606(CHEMBL1202835)
Affinity DataIC50: 228nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50366605(CHEMBL1202836)
Affinity DataIC50: 233nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50080164(5-[12-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-dodec...)
Affinity DataIC50: 434nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50342601(Huperzine A | CHEMBL1255901)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed