Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50009123
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080227(N-((S)-1-Benzyl-2-{2-[5-(3-cyano-phenyl)-thiophene...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080220((S)-3-((R)-3-Benzyloxy-2-methanesulfonylamino-prop...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080225(N-[(S)-2-(2-{5-[3-(Acetylamino-methyl)-phenyl]-thi...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080217(N-{(S)-1-Benzyl-2-oxo-2-[2-(5-pyridin-2-yl-thiophe...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080231(N-((S)-1-Benzyl-2-{2-[5-(3-formyl-phenyl)-thiophen...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080213(N-((S)-1-Benzyl-2-{2-[5-(3-morpholin-4-ylmethyl-ph...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080222(4-Methyl-pentanoic acid {(S)-1-benzyl-2-oxo-2-[2-(...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080223(N-{(S)-1-Benzyl-2-oxo-2-[2-(5-pyridin-2-yl-thiophe...)
Affinity DataKi:  26nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080229(N-{(S)-1-Benzyl-2-oxo-2-[2-(5-pyridin-2-yl-thiophe...)
Affinity DataKi:  46nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080221(N-{(S)-1-Benzyl-2-oxo-2-[2-(5-pyridin-2-yl-thiophe...)
Affinity DataKi:  49nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080219((S)-3-[2-(2,6-Dichloro-pyridin-3-yl)-acetylamino]-...)
Affinity DataKi:  57nMAssay Description:Inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080226(N-((S)-1-Benzyl-2-oxo-2-{2-[4-(4-pyridin-2-yl-pipe...)
Affinity DataKi:  59nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080224(4-Phenyl-pentanoic acid {(S)-1-benzyl-2-oxo-2-[2-(...)
Affinity DataKi:  62nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080211(N-((S)-2-{2-[4-(4-Acetyl-piperazin-1-ylmethyl)-ben...)
Affinity DataKi:  71nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080216(N-{(S)-1-Benzyl-2-oxo-2-[2-(5-pyridin-2-yl-thiophe...)
Affinity DataKi:  130nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065409((S)-3-((R)-3-Benzyloxy-2-methanesulfonylamino-prop...)
Affinity DataKi:  130nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080228((S)-3-(3-Methyl-butyrylamino)-2-oxo-4-phenyl-N-[2-...)
Affinity DataKi:  420nMAssay Description:Inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080230(N-{(S)-1-Benzyl-2-oxo-2-[2-(5-pyridin-2-yl-thiophe...)
Affinity DataKi:  430nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080215(N-{(S)-1-Benzyl-2-oxo-2-[2-(5-pyridin-2-yl-thiophe...)
Affinity DataKi:  570nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080214(Benzo[1,3]dioxole-5-carboxylic acid {(S)-1-benzyl-...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080218((S)-3-Isobutyrylamino-2-oxo-4-phenyl-N-[2-(5-pyrid...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50080212((S)-2-Oxo-4-phenyl-3-(4-phenyl-butyrylamino)-N-[2-...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed