Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 1157
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 1.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM8964(CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...)
Affinity DataIC50: 7.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9441(N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]qu...)
Affinity DataIC50: 8.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9440(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]q...)
Affinity DataIC50: 10.1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9435(N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,7-...)
Affinity DataIC50: 12.8nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9436(N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]py...)
Affinity DataIC50: 13.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9442(CHEMBL1082739 | N-[9-(1,2,3,4-tetrahydroacridin-9-...)
Affinity DataIC50: 38.7nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9433(N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,1...)
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9431(dimethyl[8-(1,2,3,4-tetrahydroacridin-9-ylamino)oc...)
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9430(dimethyl[7-(1,2,3,4-tetrahydroacridin-9-ylamino)he...)
Affinity DataIC50: 52nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9432(N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,9...)
Affinity DataIC50: 71nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9437(N-[9-(1,2,3,4-tetrahydroacridin-9-ylamino)nonyl]py...)
Affinity DataIC50: 83.6nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9426(N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...)
Affinity DataIC50: 89.4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 92nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM8964(CHEMBL75274 | N-[8-(1,2,3,4-tetrahydroacridin-9-yl...)
Affinity DataIC50: 105nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9440(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]q...)
Affinity DataIC50: 110nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9441(N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]qu...)
Affinity DataIC50: 126nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9427(CHEMBL1083790 | N-(9-aminononyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: 131nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9430(dimethyl[7-(1,2,3,4-tetrahydroacridin-9-ylamino)he...)
Affinity DataIC50: 143nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9428(N-(10-aminodecyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 147nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM8963(N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-...)
Affinity DataIC50: 149nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9442(CHEMBL1082739 | N-[9-(1,2,3,4-tetrahydroacridin-9-...)
Affinity DataIC50: 156nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9436(N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]py...)
Affinity DataIC50: 157nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9431(dimethyl[8-(1,2,3,4-tetrahydroacridin-9-ylamino)oc...)
Affinity DataIC50: 170nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9438(N-[10-(1,2,3,4-tetrahydroacridin-9-ylamino)decyl]p...)
Affinity DataIC50: 176nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9429(CHEMBL1084093 | N-(12-aminododecyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9437(N-[9-(1,2,3,4-tetrahydroacridin-9-ylamino)nonyl]py...)
Affinity DataIC50: 200nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9426(N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...)
Affinity DataIC50: 202nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 223nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9432(N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,9...)
Affinity DataIC50: 237nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9439(N-[12-(1,2,3,4-tetrahydroacridin-9-ylamino)dodecyl...)
Affinity DataIC50: 261nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9434(CHEMBL1084368 | N,N-Dimethyl-N-9-(1,2,3,4-tetrahyd...)
Affinity DataIC50: 264nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9435(N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,7-...)
Affinity DataIC50: 302nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9425(N-9-(1,2,3,4-Tetrahydroacridinyl)-1,7-diaminohepta...)
Affinity DataIC50: 319nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9425(N-9-(1,2,3,4-Tetrahydroacridinyl)-1,7-diaminohepta...)
Affinity DataIC50: 357nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9439(N-[12-(1,2,3,4-tetrahydroacridin-9-ylamino)dodecyl...)
Affinity DataIC50: 377nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9438(N-[10-(1,2,3,4-tetrahydroacridin-9-ylamino)decyl]p...)
Affinity DataIC50: 427nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9433(N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,1...)
Affinity DataIC50: 581nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9428(N-(10-aminodecyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 682nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9427(CHEMBL1083790 | N-(9-aminononyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50: 687nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9434(CHEMBL1084368 | N,N-Dimethyl-N-9-(1,2,3,4-tetrahyd...)
Affinity DataIC50: 695nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM9429(CHEMBL1084093 | N-(12-aminododecyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 791nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2006
Entry Details Article
PubMed