Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50009327
TargetNitric oxide synthase, inducible(Mouse)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM7882(CHEMBL540 | 1H-imidazole | imidazole | Imidazole (...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082309(N-(1H-Imidazol-2-ylmethyl)-guanidine | CHEMBL10131...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082307((R)-2-Amino-5-[N'-(1H-imidazol-2-ylmethyl)-guanidi...)
Affinity DataIC50: 3.47E+5nMAssay Description:Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence of 50 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082310((R)-2-Amino-5-{N'-[2-(1H-imidazol-2-yl)-ethyl]-gua...)
Affinity DataIC50: 6.29E+5nMAssay Description:Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence of 50 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50078824(2-Phenyl-1H-imidazole | CHEMBL14189 | US9138393, 2...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082308((R)-2-Amino-5-{N'-[2-(3H-imidazol-4-yl)-ethyl]-gua...)
Affinity DataIC50: 1.09E+6nMAssay Description:Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence of 50 u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082310((R)-2-Amino-5-{N'-[2-(1H-imidazol-2-yl)-ethyl]-gua...)
Affinity DataIC50: 1.49E+6nMAssay Description:Inhibition of rat neuronal nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence of 50 uM L-ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082307((R)-2-Amino-5-[N'-(1H-imidazol-2-ylmethyl)-guanidi...)
Affinity DataIC50: 1.59E+6nMAssay Description:Inhibition of rat neuronal nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence of 50 uM L-ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed