Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50035024
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082324((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082323(4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...)
Affinity DataIC50: 190nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50: 220nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50017702(cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...)
Affinity DataIC50: 228nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50017702(cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...)
Affinity DataIC50: 290nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082320(4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...)
Affinity DataIC50: 320nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082322(1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...)
Affinity DataIC50: 360nMAssay Description:Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082320(4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082323(4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50: 4.08E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082324((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50: 4.34E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082319((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)
Affinity DataIC50: 4.64E+3nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50082322(1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed