Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50009439
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083639({4-[6-((S)-3-Ethyl-piperazin-1-yl)-pyridin-3-yl]-p...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083638({4-[6-((S)-3-Methyl-piperazin-1-yl)-pyridin-3-yl]-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083649({4-[6-(3-Methyl-piperazin-1-yl)-pyridin-3-yl]-pyri...)
Affinity DataIC50: 26nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083640([4-(6-[1,4]Diazepan-1-yl-pyridin-3-yl)-pyrimidin-2...)
Affinity DataIC50: 31nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083648({4-[6-(4-Methyl-piperazin-1-yl)-pyridin-3-yl]-pyri...)
Affinity DataIC50: 46nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083644([4-(6-Piperazin-1-yl-pyridin-3-yl)-pyrimidin-2-yl]...)
Affinity DataIC50: 54nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083641(N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...)
Affinity DataIC50: 125nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50083641(N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...)
Affinity DataIC50: 150nMAssay Description:Inhibition of protein kinase C (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083642({4-[6-((S)-3-Isopropyl-piperazin-1-yl)-pyridin-3-y...)
Affinity DataIC50: 188nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083650([4-(3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-5'-yl)...)
Affinity DataIC50: 332nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083646({4-[6-((R)-3-Methyl-piperazin-1-yl)-pyridin-3-yl]-...)
Affinity DataIC50: 396nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083645([4-(6-Morpholin-4-yl-pyridin-3-yl)-pyrimidin-2-yl]...)
Affinity DataIC50: 424nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083643((4-Pyridin-3-yl-pyrimidin-2-yl)-(3,4,5-trimethoxy-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083641(N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50083644([4-(6-Piperazin-1-yl-pyridin-3-yl)-pyrimidin-2-yl]...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of protein kinase C (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50083643((4-Pyridin-3-yl-pyrimidin-2-yl)-(3,4,5-trimethoxy-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of protein kinase C (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083644([4-(6-Piperazin-1-yl-pyridin-3-yl)-pyrimidin-2-yl]...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083643((4-Pyridin-3-yl-pyrimidin-2-yl)-(3,4,5-trimethoxy-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083639({4-[6-((S)-3-Ethyl-piperazin-1-yl)-pyridin-3-yl]-p...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50083639({4-[6-((S)-3-Ethyl-piperazin-1-yl)-pyridin-3-yl]-p...)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of protein kinase C (PKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083644([4-(6-Piperazin-1-yl-pyridin-3-yl)-pyrimidin-2-yl]...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083647({4-[6-(4-Ethyl-piperazin-1-yl)-pyridin-3-yl]-pyrim...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083641(N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083644([4-(6-Piperazin-1-yl-pyridin-3-yl)-pyrimidin-2-yl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of csk tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083643((4-Pyridin-3-yl-pyrimidin-2-yl)-(3,4,5-trimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of csk tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083641(N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of csk tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083639({4-[6-((S)-3-Ethyl-piperazin-1-yl)-pyridin-3-yl]-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083639({4-[6-((S)-3-Ethyl-piperazin-1-yl)-pyridin-3-yl]-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of csk tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Celltech Therapeutics

Curated by ChEMBL
LigandPNGBDBM50083643((4-Pyridin-3-yl-pyrimidin-2-yl)-(3,4,5-trimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed