Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50009448
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50071411(1-(5-Bromo-pyridin-2-yl)-3-(2-piperidin-1-yl-ethyl...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(HI-240 | 1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-p...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM1866(N-(2-(2-Pyridylethyl))-N -(2-(5-bromopyridyl))thio...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083679(1-(2-Benzo[1,3]dioxol-5-yl-ethyl)-3-(5-bromo-pyrid...)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM2337(CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083680(1-(5-Bromo-pyridin-2-yl)-3-(2-thiophen-2-yl-ethyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM2151(1-(5-bromopyridin-2-yl)-3-[2-(1H-indol-3-yl)ethyl]...)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083678(1-(5-Bromo-pyridin-2-yl)-3-(2-furan-2-yl-ethyl)-th...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM1944(BHAP deriv. | N-[2-({4-[3-(propan-2-ylamino)pyridi...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083683(1-(5-Bromo-pyridin-2-yl)-3-(2-pyrrolidin-1-yl-ethy...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083681(1-(5-Bromo-pyridin-2-yl)-3-[2-(1H-imidazol-4-yl)-e...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083684(1-(5-Bromo-pyridin-2-yl)-3-[2-(1-methyl-pyrrolidin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50083682(1-(5-Bromo-pyridin-2-yl)-3-(2-morpholin-4-yl-ethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed