Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50009481
TargetMuscarinic acetylcholine receptor M1(Rat)
Institute of Pharmacy and Biochemistry

Curated by ChEMBL
LigandPNGBDBM50084050(3-(6-Chloro-pyridin-2-yl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M1 in rat brain cortex at 10e-5 M of compound concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Institute of Pharmacy and Biochemistry

Curated by ChEMBL
LigandPNGBDBM50084051(3-(6-Chloro-pyridin-3-yl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M1 in rat brain cortex at 10e-5 M of compound concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Institute of Pharmacy and Biochemistry

Curated by ChEMBL
LigandPNGBDBM50084053(6-Chloro-1',2',3',6'-tetrahydro-[3,4']bipyridinyl;...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of [3H]-5-HT binding to 5-hydroxytryptamine 1B receptor in rat striatum; Residual radioligand binding higher than 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Institute of Pharmacy and Biochemistry

Curated by ChEMBL
LigandPNGBDBM50084054(CHEMBL1181055 | CHEMBL154087 | 6'-Chloro-1-methyl-...)
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat heart atria at 10e-5 M of compound concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Institute of Pharmacy and Biochemistry

Curated by ChEMBL
LigandPNGBDBM50084051(3-(6-Chloro-pyridin-3-yl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat heart atria at 10e-5 M of compound concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Institute of Pharmacy and Biochemistry

Curated by ChEMBL
LigandPNGBDBM50084053(6-Chloro-1',2',3',6'-tetrahydro-[3,4']bipyridinyl;...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of [3H]8-hydroxy-2-dipropylamino-1,2,3,4-tetrahydronaphthalene binding to 5-hydroxytryptamine 1A receptor in hippocampus region of rat bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed