Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50009485
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandPNGBDBM50073922({(S)-1-[(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 5nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandPNGBDBM50084064({(S)-1-[(7-Chloro-2,3-dioxo-1,2,3,4-tetrahydro-qui...)
Affinity DataIC50: 6nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandPNGBDBM50073930({(S)-1-[(2,3-Dioxo-7-trifluoromethyl-1,2,3,4-tetra...)
Affinity DataIC50: 8nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandPNGBDBM50084062({(S)-1-[(7-Iodo-2,3-dioxo-1,2,3,4-tetrahydro-quino...)
Affinity DataIC50: 8nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandPNGBDBM50084063({(S)-1-[(7-Fluoro-2,3-dioxo-1,2,3,4-tetrahydro-qui...)
Affinity DataIC50: 9nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandPNGBDBM50073950({(S)-1-[(7-Nitro-2,3-dioxo-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 32nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandPNGBDBM50084065({(S)-1-[(7-Cyano-2,3-dioxo-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 76nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed